Ultrasound-mediated transfection enhanced by cavitation facilitation and membrane modification

Ryohei Ogawa*, Tetsuo Nozaki, Go Kagiya, Loreto B. Feril, Hideki Fuse, Takashi Kondo

*この論文の責任著者

研究成果: 書籍の章/レポート/会議録会議への寄与査読

抄録

The mechanism of ultrasound-mediated transfection (USMT) was explored to get a better understanding and improvement of the efficiency. Efficiency of USMT was linked to cavitational effects and also to plasma membrane conditions. These results indicate that the mechanism underlying USMT is possibly explained by the interaction between the cavitational effect and a plasma membrane response. When both were combined, transfection efficiency was significantly enhanced in vitro and in vivo. This enhancement could be useful for ultrasound-mediated gene therapy in the future.

本文言語英語
ホスト出版物のタイトル4th International Symposium on Therapeutic Ultrasound
ページ91-93
ページ数3
DOI
出版ステータス出版済み - 2005/03/28
イベント4th International Symposium on Therapeutic Ultrasound - Kyoto, 日本
継続期間: 2004/09/182004/09/20

出版物シリーズ

名前AIP Conference Proceedings
754
ISSN(印刷版)0094-243X
ISSN(電子版)1551-7616

学会

学会4th International Symposium on Therapeutic Ultrasound
国/地域日本
CityKyoto
Period2004/09/182004/09/20

ASJC Scopus 主題領域

  • 物理学および天文学一般

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