@article{f5a7ff27aa534a4a908a582f65ff01b3,
title = "Real-time visualization of intratumoral necrosis using split-luciferase reconstitution by protein trans-splicing",
abstract = "Necrosis occurs with the development of various diseases and in tumor tissue responding to cancer treatment. To evaluate the preclinical effectiveness of different anticancer drugs and radiation therapy, Kagiya and colleagues have constructed a real-time visualization system for intratumoral necrosis using split-luciferase reconstitution by protein trans-splicing.",
keywords = "bioluminescent imaging, cell death, extein, intein, necrosis, necrosis imaging reporter, protein trans-splicing, split-luciferase reconstitution",
author = "Go Kagiya and Ayaka Sato and Ryohei Ogawa and Masanori Hatashita and Mana Kato and Makoto Kubo and Fumiaki Kojima and Fumitaka Kawakami and Yukari Nishimura and Naoya Abe and Fuminori Hyodo",
note = "Publisher Copyright: {\textcopyright} 2020 The Author(s)",
year = "2021",
month = mar,
day = "26",
doi = "10.1016/j.omto.2020.12.001",
language = "英語",
volume = "20",
pages = "48--58",
journal = "Molecular Therapy - Oncolytics",
issn = "2372-7705",
publisher = "Cell Press",
}