Hypercalcemia and hyperphosphatemia associated with 25-OH vitamin D deficiency in an alcoholic patient with normal renal function

Tomohiko Asada; Minoru Iwata; Shigeru Matsuzaki; Hiroshi Hamakawa; Satoru Sengan; Toshifumi Noguchi; Kazushi Daimon; Naoki Matsumura; Morikazu Shibasaki; Tetsushi Tsujimoto; Ken Ooi; Hidenao Fukuyama

doi:10.1016/j.jecr.2022.100107

Hypercalcemia and hyperphosphatemia associated with 25-OH vitamin D deficiency in an alcoholic patient with normal renal function

Tomohiko Asada^*, Minoru Iwata, Shigeru Matsuzaki, Hiroshi Hamakawa, Satoru Sengan, Toshifumi Noguchi, Kazushi Daimon, Naoki Matsumura, Morikazu Shibasaki, Tetsushi Tsujimoto, Ken Ooi, Hidenao Fukuyama

^*この論文の責任著者

人間科学２講座

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

抄録

We present the case of a 55-year-old female patient with alcohol-related liver damage who presented with hypercalcemia and hyperphosphatemia but also showed severe paradoxical reduction in serum 25-OH vitamin D levels. The serum levels of 1, 25-(OH) ₂ vitamin D, parathyroid hormone, and renal function parameters were normal. Therefore, we examined the renal reabsorption of calcium and phosphate and found a mild increase in both. The serum levels of calcium and phosphate might be determined by 1, 25-(OH) ₂ vitamin D-mediated excessive renal reabsorption of calcium and phosphate in alcoholics with 25-OH vitamin D deficiency but normal renal function.

本文言語	英語
論文番号	100107
ジャーナル	Journal of Clinical and Translational Endocrinology: Case Reports
巻	23
DOI	https://doi.org/10.1016/j.jecr.2022.100107
出版ステータス	出版済み - 2022/03

ASJC Scopus 主題領域

内分泌学、糖尿病および代謝内科学
内分泌学

UN SDG

この成果は、次の持続可能な開発目標に貢献しています

文献へのアクセス

10.1016/j.jecr.2022.100107

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引用スタイル

Asada, T., Iwata, M., Matsuzaki, S., Hamakawa, H., Sengan, S., Noguchi, T., Daimon, K., Matsumura, N., Shibasaki, M., Tsujimoto, T., Ooi, K., & Fukuyama, H. (2022). Hypercalcemia and hyperphosphatemia associated with 25-OH vitamin D deficiency in an alcoholic patient with normal renal function. Journal of Clinical and Translational Endocrinology: Case Reports, 23, 記事 100107. https://doi.org/10.1016/j.jecr.2022.100107

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title = "Hypercalcemia and hyperphosphatemia associated with 25-OH vitamin D deficiency in an alcoholic patient with normal renal function",

abstract = "We present the case of a 55-year-old female patient with alcohol-related liver damage who presented with hypercalcemia and hyperphosphatemia but also showed severe paradoxical reduction in serum 25-OH vitamin D levels. The serum levels of 1, 25-(OH) 2 vitamin D, parathyroid hormone, and renal function parameters were normal. Therefore, we examined the renal reabsorption of calcium and phosphate and found a mild increase in both. The serum levels of calcium and phosphate might be determined by 1, 25-(OH) 2 vitamin D-mediated excessive renal reabsorption of calcium and phosphate in alcoholics with 25-OH vitamin D deficiency but normal renal function.",

keywords = "25-OH vitamin D deficiency, Alcoholic liver damage, Alcoholic patient, Excessive renal reabsorption, Hypercalcemia with hyperphosphatemia, Normal renal function",

author = "Tomohiko Asada and Minoru Iwata and Shigeru Matsuzaki and Hiroshi Hamakawa and Satoru Sengan and Toshifumi Noguchi and Kazushi Daimon and Naoki Matsumura and Morikazu Shibasaki and Tetsushi Tsujimoto and Ken Ooi and Hidenao Fukuyama",

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Asada, T, Iwata, M, Matsuzaki, S, Hamakawa, H, Sengan, S, Noguchi, T, Daimon, K, Matsumura, N, Shibasaki, M, Tsujimoto, T, Ooi, K & Fukuyama, H 2022, 'Hypercalcemia and hyperphosphatemia associated with 25-OH vitamin D deficiency in an alcoholic patient with normal renal function', Journal of Clinical and Translational Endocrinology: Case Reports, vol. 23, 100107. https://doi.org/10.1016/j.jecr.2022.100107

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T1 - Hypercalcemia and hyperphosphatemia associated with 25-OH vitamin D deficiency in an alcoholic patient with normal renal function

AU - Asada, Tomohiko

AU - Iwata, Minoru

AU - Matsuzaki, Shigeru

AU - Hamakawa, Hiroshi

AU - Sengan, Satoru

AU - Noguchi, Toshifumi

AU - Daimon, Kazushi

AU - Matsumura, Naoki

AU - Shibasaki, Morikazu

AU - Tsujimoto, Tetsushi

AU - Ooi, Ken

AU - Fukuyama, Hidenao

PY - 2022/3

Y1 - 2022/3

N2 - We present the case of a 55-year-old female patient with alcohol-related liver damage who presented with hypercalcemia and hyperphosphatemia but also showed severe paradoxical reduction in serum 25-OH vitamin D levels. The serum levels of 1, 25-(OH) 2 vitamin D, parathyroid hormone, and renal function parameters were normal. Therefore, we examined the renal reabsorption of calcium and phosphate and found a mild increase in both. The serum levels of calcium and phosphate might be determined by 1, 25-(OH) 2 vitamin D-mediated excessive renal reabsorption of calcium and phosphate in alcoholics with 25-OH vitamin D deficiency but normal renal function.

AB - We present the case of a 55-year-old female patient with alcohol-related liver damage who presented with hypercalcemia and hyperphosphatemia but also showed severe paradoxical reduction in serum 25-OH vitamin D levels. The serum levels of 1, 25-(OH) 2 vitamin D, parathyroid hormone, and renal function parameters were normal. Therefore, we examined the renal reabsorption of calcium and phosphate and found a mild increase in both. The serum levels of calcium and phosphate might be determined by 1, 25-(OH) 2 vitamin D-mediated excessive renal reabsorption of calcium and phosphate in alcoholics with 25-OH vitamin D deficiency but normal renal function.

KW - 25-OH vitamin D deficiency

KW - Alcoholic liver damage

KW - Alcoholic patient

KW - Excessive renal reabsorption

KW - Hypercalcemia with hyperphosphatemia

KW - Normal renal function

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