Boron Trifluoride-Mediated Domino Dehydration/Electrophilic Cyclization of Silylalkynols Leading to 2,3-Fused Tricyclic Benzofulvenes

Takashi Okitsu; Takeshi Yoshikawa; Mai Morohashi; Kokoro Aoki; Takayuki Yakura; Ken Sakata; Manabu Hatano

doi:10.1021/acs.orglett.4c00123

Boron Trifluoride-Mediated Domino Dehydration/Electrophilic Cyclization of Silylalkynols Leading to 2,3-Fused Tricyclic Benzofulvenes

Takashi Okitsu^*
, Takeshi Yoshikawa^*
, Mai Morohashi
, Kokoro Aoki
, Takayuki Yakura
, Ken Sakata
, Manabu Hatano

^*この論文の責任著者

分子合成化学研究室

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

1 被引用数 (Scopus)

抄録

A BF₃-mediated domino dehydration/electrophilic cyclization of silylalkynols to form 2,3-fused tricyclic benzofulvenes was achieved. In the latter step, in situ generated BF₃·OH₂ enables the electrophilic activation of alkynes. The predominant Z-selectivity of the reaction is also discussed.

本文言語	英語
ページ（範囲）	1652-1656
ページ数	5
ジャーナル	Organic Letters
巻	26
号	8
DOI	https://doi.org/10.1021/acs.orglett.4c00123
出版ステータス	出版済み - 2024/03/01

ASJC Scopus 主題領域

生化学
物理化学および理論化学
有機化学

文献へのアクセス

10.1021/acs.orglett.4c00123

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引用スタイル

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abstract = "A BF3-mediated domino dehydration/electrophilic cyclization of silylalkynols to form 2,3-fused tricyclic benzofulvenes was achieved. In the latter step, in situ generated BF3·OH2 enables the electrophilic activation of alkynes. The predominant Z-selectivity of the reaction is also discussed.",

author = "Takashi Okitsu and Takeshi Yoshikawa and Mai Morohashi and Kokoro Aoki and Takayuki Yakura and Ken Sakata and Manabu Hatano",

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AU - Okitsu, Takashi

AU - Yoshikawa, Takeshi

AU - Morohashi, Mai

AU - Aoki, Kokoro

AU - Yakura, Takayuki

AU - Sakata, Ken

AU - Hatano, Manabu

PY - 2024/3/1

Y1 - 2024/3/1

N2 - A BF3-mediated domino dehydration/electrophilic cyclization of silylalkynols to form 2,3-fused tricyclic benzofulvenes was achieved. In the latter step, in situ generated BF3·OH2 enables the electrophilic activation of alkynes. The predominant Z-selectivity of the reaction is also discussed.

AB - A BF3-mediated domino dehydration/electrophilic cyclization of silylalkynols to form 2,3-fused tricyclic benzofulvenes was achieved. In the latter step, in situ generated BF3·OH2 enables the electrophilic activation of alkynes. The predominant Z-selectivity of the reaction is also discussed.

UR - https://www.scopus.com/pages/publications/85186181056

U2 - 10.1021/acs.orglett.4c00123

DO - 10.1021/acs.orglett.4c00123

M3 - 学術論文

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AN - SCOPUS:85186181056

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JO - Organic Letters

JF - Organic Letters

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