Binge alcohol consumption aggravates oxidative stress and promotes pathogenesis of NASH from obesity-induced simple steatosis

Keyphrases

• Nonalcoholic Steatohepatitis 100%
• Obesity 100%
• Oxidative Stress 100%
• Binge Drinking 100%
• Simple Steatosis 100%
• Ethanol 83%
• Otsuka Long-Evans Tokushima Fatty Rat 83%
• Cytochrome P450 2E1 (CYP2E1) 66%
• 4-hydroxynonenal (4-HNE) 33%
• Steatosis 33%
• Long-Evans 33%
• Binge 33%
• Tokushima 33%
• Liver 16%
• Insulin Resistance 16%
• Triglyceride Level 16%
• Steatohepatitis 16%
• Serum Samples 16%
• Alcohol 16%
• Tumor Necrosis Factor-α 16%
• Liver Specimen 16%
• Hyperglycemia 16%
• Serum Triglycerides 16%
• Histopathological Changes 16%
• Aggravation 16%
• Young Males 16%
• Hepatic Fat 16%
• Hyperinsulinemia 16%
• Two-stage Process 16%
• Liver Sections 16%
• Hypertriglycemia 16%
• Hepatic Tissue 16%
• Biochemical Parameters 16%
• Hepatocyte Ballooning 16%

Medicine and Dentistry

• Nonalcoholic Fatty Liver 100%
• Oxidative Stress 100%
• Alcohol Consumption 100%
• Steatosis 100%
• Alcohol 83%
• Cytochrome 66%
• 4 Hydroxynonenal 33%
• Insulin Resistance 16%
• Steatohepatitis 16%
• Triacylglycerol 16%
• Tumor Necrosis Factor 16%
• Hepatocyte 16%
• Hyperglycemia 16%
• Hyperinsulinemia 16%
• Messenger RNA 16%

Pharmacology, Toxicology and Pharmaceutical Science

• Nonalcoholic Fatty Liver 100%
• Ethanol 100%
• Steatosis 100%
• Otsuka Long Evans Tokushima Fatty Rat 100%
• Cytochrome 57%
• 4 Hydroxynonenal 28%
• Insulin Resistance 14%
• Triacylglycerol 14%
• Tumor Necrosis Factor 14%
• Hyperglycemia 14%
• Hyperinsulinemia 14%
• Messenger RNA 14%