Takeshi Kodama

2024

A new 3,4-seco-isopimarane and three new isopimarane diterpenoids from Kaempferia champasakensis collected from Vietnam and their cytotoxic activities

Do, K. M., Hoshino, S., Kodama, T., Nguyen, H. M., Van Le, S., Ikumi, N., Onaka, H. & Morita, H., 2024, (受理済み/印刷中) In: Natural Medicines.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

1 被引用数 (Scopus)

Cytotoxic potential of dihydrochalcones from Eriosema glomeratum and their semi-synthetic derivatives

Tabakam, G. T., Kodama, T., Tchuenmogne, M. A. T., Hoang, N. N., Nomin-Erdene, B., Ngouela, S. A., Tene, M., Morita, H. & Awouafack, M. D., 2024, In: Natural Product Research. 38, 2, p. 186-197 12 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

1 被引用数 (Scopus)

Five pimarane diterpenoids from Kaempferia champasakensis and their cytotoxic activities

Do, K. M., Hoshino, S., Kodama, T., Nguyen, H. M., Ikumi, N., Onaka, H. & Morita, H., 2024/09, In: Natural Medicines. 78, 4, p. 908-918 11 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

New 19(10 → 9)abeo-euphane-type triterpenoids from Trichilia dregeana leaves and NO production inhibitory activities

Mba Nguekeu, Y. M., Kodama, T., Tsepeupon Matchide, M. G., Do, K. M., Nghokeng, J., Tabakam, G. T., Tsuge, K., Ngouela, S. A., Mathieu, T., Awouafack, M. D. & Morita, H., 2024/07, In: Fitoterapia. 176, 106001.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Substrate-Dependent Alteration in the C- and O-Prenylation Specificities of Cannabis Prenyltransferase

Tanaya, R., Kodama, T., Maneenet, J., Yasuno, Y., Nakayama, A., Shinada, T., Takahashi, H., Ito, T., Morita, H., Awale, S. & Taura, F., 2024/02, In: Biological and Pharmaceutical Bulletin. 47, 2, p. 449-453 5 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

Three neo-Clerodane Diterpenoids from Tinospora cordifolia Stems and Their Arginase Inhibitory Activities

Hoang, N. N., Hoshino, S., Kodama, T., Nakashima, Y., Do, K. M., Thao, H. X., Ikumi, N., Onaka, H. & Morita, H., 2024/06, In: Chemical and Pharmaceutical Bulletin. 72, 6, p. 540-546 7 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

1 被引用数 (Scopus)

2023

Arginase inhibitory activities of guaiane sesquiterpenoids from Curcuma comosa rhizomes

Hoang, N. N., Kodama, T., Nakashima, Y., Do, K. M., Hnin, S. Y. Y., Lee, Y. E., Prema, Ikumi, N. & Morita, H., 2023/09, In: Natural Medicines. 77, 4, p. 891-897 7 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

2 被引用数 (Scopus)

Catalytic Potential of Cannabis Prenyltransferase to Expand Cannabinoid Scaffold Diversity

Tanaya, R., Kodama, T., Lee, Y. E., Yasuno, Y., Shinada, T., Takahashi, H., Ito, T., Morita, H., Awale, S. & Taura, F., 2023/12/08, In: Organic Letters. 25, 48, p. 8601-8605 5 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

2 被引用数 (Scopus)

Novel insights into the antibacterial activities of cannabinoid biosynthetic intermediate, olivetolic acid, and its alkyl-chain derivatives

Lee, Y. E., Kodama, T. & Morita, H., 2023/03, In: Natural Medicines. 77, 2, p. 298-305 8 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

7 被引用数 (Scopus)

Phenolic Derivatives with Anti-Acetylcholinesterase Inhibitory Activities from Galeola nudifolia in Vietnam

Do, K. M., Nakashima, Y., Kodama, T., Lee, Y. E., Nguyen, H. M., Ikumi, N. & Morita, H., 2023/12, In: Chemistry and Biodiversity. 20, 12, e202301482.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

1 被引用数 (Scopus)

Seco- and isopimarane diterpenoids from Kaempferia marginata rhizomes and their NO inhibition activities

Do, K. M., Kodama, T., Nguyen, H. M., Ikumi, N., Soeda, C., Shiokawa, K. I. & Morita, H., 2023/01, In: Phytochemistry. 205, 113510.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

2 被引用数 (Scopus)

2022

A New Sterol From the Polypore Fungus Ganoderma luteomarginatum and Its Cytotoxic Activities

Htoo, Z. P., Kodama, T., Win, N. N., Ikumi, N., Shiokawa, K. I. & Morita, H., 2022/05, In: Natural Product Communications. 17, 5

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

Bioinspired computational design of lankacidin derivatives for improvement in antitumor activity

Ayoub, A. T., Nishiura, N., Teshima, A., Elrefaiy, M. A., Muslimin, R., Do, K. M., Kodama, T., Lewis, C. W., Chan, G., Morita, H. & Arakawa, K., 2022/10/01, In: Future Medicinal Chemistry. 14, 19, p. 1349-1360 12 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

2 被引用数 (Scopus)

Catalytic potential of a fungal indole prenyltransferase toward β-carbolines, harmine and harman, and their prenylation effects on antibacterial activity

Hamdy, S. A., Kodama, T., Nakashima, Y., Han, X. & Morita, H., 2022/10, In: Journal of Bioscience and Bioengineering. 134, 4, p. 311-317 7 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

2 被引用数 (Scopus)

Chemoenzymatic synthesis, computational investigation, and antitumor activity of monocyclic lankacidin derivatives

Muslimin, R., Nishiura, N., Teshima, A., Do, K. M., Kodama, T., Morita, H., Lewis, C. W., Chan, G., Ayoub, A. T. & Arakawa, K., 2022/01/01, In: Bioorganic and Medicinal Chemistry. 53

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Chemoenzymatic synthesis, computational investigation, and antitumor activity of monocyclic lankacidin derivatives

Muslimin, R., Nishiura, N., Teshima, A., Do, K. M., Kodama, T., Morita, H., Lewis, C. W., Chan, G., Ayoub, A. T. & Arakawa, K., 2022/01/01, In: Bioorganic and Medicinal Chemistry. 53, 116551.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

2 被引用数 (Scopus)

Divergent synthesis of decahydroquinoline-type poison-frog alkaloids.

寄稿の翻訳タイトル: Divergent synthesis of decahydroquinoline-type poison-frog alkaloids.Takashima, K., Okada, T., Kato, A., Yamasaki, Y., Sugouchi, T., Akanuma, S.-I., Kubo, Y., Hosoya, K.-I., Morita, H., Ito, T., Kodama, T., Tanabe, G. & Toyooka, N., 2022/02, In: ChemistrySelect. 7, 5

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

3 被引用数 (Scopus)

Dual Engineering of Olivetolic Acid Cyclase and Tetraketide Synthase to Generate Longer Alkyl-Chain Olivetolic Acid Analogs

Lee, Y. E., Nakashima, Y., Kodama, T., Chen, X. & Morita, H., 2022/01/14, In: Organic Letters. 24, 1, p. 410-414 5 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Dual Engineering of Olivetolic Acid Cyclase and Tetraketide Synthase to Generate Longer Alkyl-Chain Olivetolic Acid Analogs

Lee, Y. E., Nakashima, Y., Kodama, T., Chen, X. & Morita, H., 2022/01/14, In: Organic Letters. 24, 1, p. 410-414 5 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

8 被引用数 (Scopus)

Enzymatic formation of a prenyl β-carboline by a fungal indole prenyltransferase

Hamdy, S. A., Kodama, T., Nakashima, Y., Han, X., Matsui, T. & Morita, H., 2022/09, In: Natural Medicines. 76, 4, p. 873-879 7 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

3 被引用数 (Scopus)

Flavanols and Flavanes from Crinum asiaticum and Their Effects on LPS Signaling Pathway Through the Inhibition of NF- κ B Activation

Do, K. M., Shin, M. K., Kodama, T., Win, N. N., Prema, P., Nguyen, H. M., Hayakawa, Y. & Morita, H., 2022/09/02, In: Planta Medica. 88, 11, p. 913-920 8 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

3 被引用数 (Scopus)

Identification of a diarylpentanoid-producing polyketide synthase revealing an unusual biosynthetic pathway of 2-(2-phenylethyl)chromones in agarwood

Wang, X. H., Gao, B. W., Nakashima, Y., Mori, T., Zhang, Z. X., Kodama, T., Lee, Y. E., Zhang, Z. K., Wong, C. P., Liu, Q. Q., Qi, B. W., Wang, J., Li, J., Liu, X., Abe, I., Morita, H., Tu, P. F. & Shi, S. P., 2022/12, In: Nature Communications. 13, 1, 348.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

39 被引用数 (Scopus)

Marginols A‒H, unprecedented pimarane diterpenoids from Kaempferia marginata and their NO inhibitory activities

Do, K. M., Kodama, T., Shin, M. K., Nu, L. H. T., Nguyen, H. M., Dang, S. V., Shiokawa, K. I., Hayakawa, Y. & Morita, H., 2022/04, In: Phytochemistry. 196, 113109.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

9 被引用数 (Scopus)

2021

A new caffeic acid ester and a new ceramide from the roots of Eriosema glomeratum

Tabakam, G. T., Kodama, T., Donfack, A. R. N., Nguekeu, Y. M. M., Nomin-Erdene, B., Htoo, Z. P., Do, K. M., Ngouela, S. A., Tene, M., Morita, H. & Awouafack, M. D., 2021/10, In: Phytochemistry Letters. 45, p. 82-87 6 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

8 被引用数 (Scopus)

A New Monoterpene from the Rhizomes of Alpinia galanga and Its Anti-Vpr Activity

Nam Hoang, N., Kodama, T., Nwet Win, N., Prema, Minh Do, K., Abe, I. & Morita, H., 2021/10, In: Chemistry and Biodiversity. 18, 10, e2100401.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

9 被引用数 (Scopus)

Anti-Vpr activities of sesqui- and diterpenoids from the roots and rhizomes of Kaempferia candida

Prema, Kodama, T., Nyunt, H. H. W., Ngwe, H., Abe, I. & Morita, H., 2021/06, In: Natural Medicines. 75, 3, p. 489-498 10 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

3 被引用数 (Scopus)

Flavonoids from Woodfordia fruticosa as potential SmltD inhibitors in the alternative biosynthetic pathway of peptidoglycan

Lee, Y. E., Kodama, T., Win, N. N., Ki, D. W., Hoang, N. N., Wong, C. P., Lae, K. Z. W., Ngwe, H., Dairi, T. & Morita, H., 2021/03/15, In: Bioorganic and Medicinal Chemistry Letters. 36, 127787.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

1 被引用数 (Scopus)

Pyrrolactams from marine sponge stylissa massa collected from myanmar and their anti-vpr activities

Win, N. N., Kodama, T., Aye, A. A., Lae, K. Z. W., Ngwe, H., Han, N. M., Abe, I. & Morita, H., 2021/07/01, In: Chemical and Pharmaceutical Bulletin. 69, 7, p. 702-705 4 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

4 被引用数 (Scopus)

Shanpanootols A-F, diterpenoids from Kaempferia pulchra rhizomes collected in Myanmar and their Vpr inhibitory activities

Win, N. N., Kodama, T., Htoo, Z. P., Hnin, S. Y. Y., Ngwe, H., Abe, I. & Morita, H., 2021/06, In: Fitoterapia. 151, 104870.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

8 被引用数 (Scopus)

Shanpanootols g and h, diterpenoids from the rhizomes of kaempferia pulchra collected in myanmar and their vpr inhibitory activities

Win, N. N., Kodama, T., Htoo, Z. P., Hnin, S. Y. Y., Ngwe, H., Abe, I. & Morita, H., 2021/09/01, In: Chemical and Pharmaceutical Bulletin. 69, 9, p. 913-917 5 p.

研究成果: ジャーナルへの寄稿 › 総説 › 査読

Open Access

3 被引用数 (Scopus)

2020

Anti-Vpr activities of homodrimane sesquiterpenoids and labdane diterpenoids from Globba sherwoodiana rhizomes

Prema, Kodama, T., Wong, C. P., El-Desoky, A. H., Nyunt, H. H. W., Ngwe, H., Abe, I. & Morita, H., 2020/10, In: Fitoterapia. 146, 104705.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

4 被引用数 (Scopus)

Chemical Constituents of the Vietnamese Marine Sponge Gelliodes sp. and Their Cytotoxic Activities

Ki, D. W., Kodama, T., El-Desoky, A. H., Wong, C. P., Nguyen, H. M., Do, K. M., Thai, Q. M., Ton Nu, L. H. & Morita, H., 2020/09/01, In: Chemistry and Biodiversity. 17, 9, e2000303.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

5 被引用数 (Scopus)

Environmentally Friendly Syntheses of Imines Applying the Pressure Reduction Technique: Reaction Cases of Less Reactive Amines and Studies by Computational Chemistry

Suzuki, S., Ito, H., Noike, M., Ishizuka, S., Nonaka, R., Funaki, K., Kodama, T., Sakaki, S., Nishino, T., Ito, M., Takahasi, T. & Yokoyama, Y., 2020, In: Green and Sustainable Chemistry. 10, 01, p. 1-17 17 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

New cytotoxic polyacetylene amides from the Egyptian marine sponge Siphonochalina siphonella

Ki, D. W., El-Desoky, A. H., Kodama, T., Wong, C. P., Ghani, M. A., El-Beih, A. A., Mizuguchi, M. & Morita, H., 2020/04, In: Fitoterapia. 142, 104511.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

10 被引用数 (Scopus)

Three new quassinoids isolated from the wood of Picrasma javanica and their anti-Vpr activities

Prema, Wong, C. P., Kodama, T., Nugroho, A. E., El-Desoky, A. H., Awouafack, M. D., Win, Y. Y., Ngwe, H., Abe, I., Morita, H. & Morita, H., 2020/06/01, In: Natural Medicines. 74, 3, p. 571-578 8 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

14 被引用数 (Scopus)

2019

Bis-iridoid and iridoid glycosides: Viral protein R inhibitors from Picrorhiza kurroa collected in Myanmar

Win, N. N., Kodama, T., Lae, K. Z. W., Win, Y. Y., Ngwe, H., Abe, I. & Morita, H., 2019/04, In: Fitoterapia. 134, p. 101-107 7 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

30 被引用数 (Scopus)

Perfect Solvent- and Catalyst-Free Syntheses of Imine Derivatives Using the Pressure Reduction Technique

Suzuki, S., Ito, H., Ishizuka, S., Nonaka, R., Noike, M., Kodama, T., Funaki, K., Taguchi, M., Kagaya, T., Sato, S., Redler, G. & Yokoyama, Y., 2019, In: Green and Sustainable Chemistry. 09, 04, p. 105-118 14 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

2017

2-Alkylquinolone alkaloid biosynthesis in the medicinal plant Evodia rutaecarpa involves collaboration of two novel type III polyketide synthases

Matsui, T., Kodama, T., Mori, T., Tadakoshi, T., Noguchi, H., Abe, I. & Morita, H., 2017/06/02, In: Journal of Biological Chemistry. 292, 22, p. 9117-9135 19 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

14 被引用数 (Scopus)

A kaempferol triglycoside from Tephrosia preussii Taub. (Fabaceae)

Mba Nguekeu, Y. M., Awouafack, M. D., Tane, P., Nguedia Lando, M. R., Kodama, T. & Morita, H., 2017, In: Natural Product Research. 31, 21, p. 2520-2526 7 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

5 被引用数 (Scopus)

Antibacterial activities of chemical constituents from the aerial parts of Hedyotis pilulifera

Nguyen, H. T., Ho, D. V., Vo, H. Q., Le, A. T., Nguyen, H. M., Kodama, T., Ito, T., Morita, H. & Raal, A., 2017, In: Pharmaceutical Biology. 55, 1, p. 787-791 5 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

20 被引用数 (Scopus)

Cycloartane-type triterpene glycosides anopanins A-C with monoacyldigalactosylglycerols from Anodendron paniculatum

Ho, V. D., Hoang, T. N. H., Vo, Q. H., Phan, V. K., Le, T. A., Pham, V. T., Nguyen, M. H., Kodama, T., Ito, T., Morita, H., Raal, A. & Nguyen, T. H., 2017/12, In: Phytochemistry. 144, p. 113-118 6 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

8 被引用数 (Scopus)

Identification and characterization of daurichromenic acid synthase active in anti-HIV biosynthesis

Iijima, M., Munakata, R., Takahashi, H., Kenmoku, H., Nakagawa, R., Kodama, T., Asakawa, Y., Abe, I., Yazaki, K., Kurosaki, F. & Taura, F., 2017/08/02, In: Plant Physiology. 174, 4, p. 2213-2230 18 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

24 被引用数 (Scopus)

Syntheses of benzophenone-xanthone hybrid polyketides and their antibacterial activities

Kodama, T., Ito, T., Dibwe, D. F., Woo, S. Y. & Morita, H., 2017, In: Bioorganic and Medicinal Chemistry Letters. 27, 11, p. 2397-2400 4 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

16 被引用数 (Scopus)

Total Syntheses of Lepadiformine Marine Alkaloids with Enantiodivergency, Utilizing Hg(OTf)₂-Catalyzed Cycloisomerization Reaction and their Cytotoxic Activities

Nishikawa, K., Yamauchi, K., Kikuchi, S., Ezaki, S., Koyama, T., Nokubo, H., Matsumura, K., Kodama, T., Kumagai, M. & Morimoto, Y., 2017/07/18, In: Chemistry - A European Journal. 23, 40, p. 9535-9545 11 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

17 被引用数 (Scopus)

Total Synthesis of the Cytotoxic Marine Triterpenoid Isodehydrothyrsiferol Reveals Partial Enantiodivergency in the Thyrsiferol Family of Natural Products

Hoshino, A., Nakai, H., Morino, M., Nishikawa, K., Kodama, T., Nishikibe, K. & Morimoto, Y., 2017/03/06, In: Angewandte Chemie - International Edition. 56, 11, p. 3064-3068 5 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

12 被引用数 (Scopus)

2016

A new cycloartane-type triterpene and a new eicosanoic acid ester from fruits of Paullinia pinnata L.

Awouafack, M. D., Ito, T., Tane, P., Kodama, T., Tanaka, M., Asakawa, Y. & Morita, H., 2016/03/01, In: Phytochemistry Letters. 15, p. 220-224 5 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

11 被引用数 (Scopus)

A new iridoid from the aerial parts of Hedyotis pilulifera

Hoai, N. T., Duc, H. V., Phu, N. D. Q., Kodama, T., Ito, T. & Morita, H., 2016/03, In: Natural Product Communications. 11, 3, p. 365-367 3 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

5 被引用数 (Scopus)

Isopimarane diterpenoids from Kaempferia pulchra rhizomes collected in Myanmar and their Vpr inhibitory activity

Win, N. N., Ito, T., Matsui, T., Aimaiti, S., Kodama, T., Ngwe, H., Okamoto, Y., Tanaka, M., Asakawa, Y., Abe, I. & Morita, H., 2016, In: Bioorganic and Medicinal Chemistry Letters. 26, 7, p. 1789-1793 5 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

39 被引用数 (Scopus)

New acylphloroglucinol derivatives from the leaves of Baeckea frutescens

Nisa, K., Ito, T., Subehan, Matsui, T., Kodama, T. & Morita, H., 2016/03/01, In: Phytochemistry Letters. 15, p. 42-45 4 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

25 被引用数 (Scopus)

New antibacterial sesquiterpene aminoquinones from a Vietnamese marine sponge of Spongia sp.

Nguyen, H. M., Ito, T., Win, N. N., Kodama, T., Hung, V. Q., Nguyen, H. T. & Morita, H., 2016/09/01, In: Phytochemistry Letters. 17, p. 288-292 5 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

17 被引用数 (Scopus)

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