薬剤部

Keyphrases

1. Iminosugars 100%
2. Glycosidase Inhibition 62%
3. Glucosidase 54%
4. Glycosidase 49%
5. Imino 39%
6. β-Galactosidase (β-Gal) 36%
7. Potent Inhibitor 34%
8. Calystegines 28%
9. Inhibitory Activity 28%
10. Alkaloids 27%
11. Glycosidase Inhibitors 27%
12. Pyrrolidine 27%
13. 1-deoxynojirimycin 27%
14. α-glucosidase Inhibitor 24%
15. Polyhydroxylated 24%
16. Pharmacological Chaperone 22%
17. Biological Evaluation 21%
18. IC50 Value 20%
19. Stereoisomers 19%
20. Alkyl 18%
21. IC50 17%
22. Fabry Disease 17%
23. Total Synthesis 16%
24. Synthetic Evaluation 16%
25. Azepane 16%
26. Methyl 16%
27. Cyclic Nitrones 15%
28. Glucocerebrosidase 15%
29. Hyacinthacine 14%
30. Gaucher Disease 14%
31. Azetidine 13%
32. Mannitol 12%
33. Asymmetric Synthesis 12%
34. Competitive Inhibitor 12%
35. Acetamido 12%
36. Mannosidase 12%
37. Maltase 11%
38. Natural Products 11%
39. Side Chain 11%
40. Biological Activity 11%
41. Pyrrolizidine 11%
42. Bicyclol 10%
43. Fagomine 10%
44. Fucosidase 10%
45. Glucuronolactone 10%
46. Sucrase 10%
47. Amides 10%
48. Hydroxymethyl 10%
49. Glycogen Phosphorylase 9%
50. Swainsonine 9%
51. Enantiomeric 9%
52. Alkyl Chain 9%
53. Aldose Reductase 9%
54. β-N-acetylhexosaminidase 9%
55. Selective Inhibitor 9%
56. Inhibitory Effect 8%
57. Fluorinated 8%
58. SAR Study 8%
59. Looking Glass 8%
60. Overall Yield 8%
61. α-glucosidase Inhibition 8%
62. α-L-rhamnosidase 8%
63. β-hexosaminidase 8%
64. Structure-activity Relationship 8%
65. Lactones 8%
66. Epimer 8%
67. Amino Acids 8%
68. Endoplasmic Reticulum 8%
69. Miglitol 8%
70. Proline 8%
71. Butyl 7%
72. Active Sites 7%
73. Docking Studies 7%
74. Nitrones 7%
75. Pyrrolidine Alkaloids 7%
76. Allyl 7%
77. Benzyl 7%
78. In Vitro Inhibition 7%
79. Castanospermum Australe 7%
80. Pyrrolizidine Alkaloids 7%
81. Carboxylic Acids 7%
82. Trehalase 7%
83. Ring-closing Metathesis 7%
84. Epimeric 6%
85. Acetic Acid 6%
86. Broussonetines 6%
87. Isomaltase 6%
88. General Synthesis 6%
89. Fluorinated Derivatives 6%
90. Oxaliplatin 6%
91. Naringinase 6%
92. Steviamine 6%
93. Flavonoids 6%
94. Stereoselectivity 6%
95. CFTR mutations 6%
96. Nojirimycin 6%
97. Mouse Model 6%
98. Isofagomine 6%
99. Convolvulaceae 6%
100. Piperidine 6%

Pharmacology, Toxicology and Pharmaceutical Science

1. Glucosidase 82%
2. Iminosugar 79%
3. Glycosidase 56%
4. IC50 39%
5. Galactosidase 37%
6. Pyrrolidine Derivative 35%
7. 1-Deoxynojirimycin 24%
8. Pharmacological Chaperone 21%
9. Natural Product 20%
10. Glucosylceramidase 18%
11. Nitrone 16%
12. Structure Activity Relationship 16%
13. Alpha Glucosidase 15%
14. Glycosidase Inhibitor 15%
15. Mannitol 13%
16. Fabry Disease 13%
17. Alpha Levo Fucosidase 12%
18. Glycogen Phosphorylase 12%
19. Azetidine 11%
20. Gaucher's Disease 11%
21. Pyrrolizidine 11%
22. Biological Activity 11%
23. Competitive Inhibitor 11%
24. Amino Acid 10%
25. Carboxamide 10%
26. Glycoside 10%
27. Arabinitol 10%
28. Galactose 10%
29. Sucrase 9%
30. Beta N Acetylhexosaminidase 9%
31. Trehalase 9%
32. Miglitol 8%
33. Swainsonine 8%
34. Sorbitol 8%
35. Hyperglycemia 7%
36. Acetylglucosaminidase 7%
37. Beta Glucuronidase 7%
38. Mannosidase 7%
39. Aldehyde Reductase 6%
40. Morus 6%
41. Castanospermum 6%
42. Pyrrolizidine Alkaloid 6%
43. 1 Deoxymannonojirimycin 6%
44. Proline 6%
45. Scilla 6%
46. Acetic Acid Derivative 6%
47. Carboxylate 6%
48. Fagomine 6%
49. Oxaliplatin 6%
50. Lysosome Storage Disease 6%
51. Convolvulaceae 5%
52. Migalastat 5%
53. Hyacinthaceae 5%
54. Piperidine 5%
55. Mouse Model 5%
56. 2,5-Dimethoxy-4-iodoamphetamine 5%
57. Aminoalcohol 5%
58. Oligo 1,6 Glucosidase 5%
59. Carbon 13 5%
60. Indolizidine Alkaloid 5%
61. Functional Groups 5%
62. Allyl 5%
63. Non Insulin Dependent Diabetes Mellitus 5%