Two cases of hepatic angiomyolipoma with difficulty for imaging differential diagnosis with hepatocellular carcinoma

Iori Motoo; Terumi Takahara; Koushi Matsui; Hideto Kawabe; Kengo Kawai; Kazuto Taziri; Yoshimitsu Tokimitsu; Satoshi Yasumura; Masami Minemura; Shigeharu Miwa; Koichi Tsuneyama; Toshiro Sugiyama; Kazuhiro Tsukada

doi:10.2957/kanzo.54.143

Two cases of hepatic angiomyolipoma with difficulty for imaging differential diagnosis with hepatocellular carcinoma

Iori Motoo, Terumi Takahara^*, Koushi Matsui, Hideto Kawabe, Kengo Kawai, Kazuto Taziri, Yoshimitsu Tokimitsu, Satoshi Yasumura, Masami Minemura, Shigeharu Miwa, Koichi Tsuneyama, Toshiro Sugiyama, Kazuhiro Tsukada

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Casel was a 79-year-old male with liver tumor. Dynamic CT showed a high density lesion in early phase and low in equilibrant phase. Gd-EOB-DTPA-enhanced MRI showed a high intensitylesioninarterial phase and a low intensity lesion in hepatobiliary phase. US-guided biopsy led to histopathological diagnosis as hepatic an-giomyolipoma. Case2 was a 40-year-old with liver tumor. Dynamic CT showed a high density lesion in early phase, low with coronal enhancement in portal phase and low in equilibrant phase. Gd-EOB-DTPA-enhanced MRI showed a high intensity area in arterial phase, low with coronal enhancement in portal phase and low in hepatobiliary phase. Both CT and MRI showed peritumoral coronal enhancement in portal phase. Histological diagnosis ofla-paroscopic surgery was hepatic angiomyolipoma. Immunohistochemical examination showed OATP was negative in the tumor but the cellular membranes of adjacent normal hepatocytes were positive. We also detected immunostaining of CD34 in the dilated vessels in fibrous capsule around the tumor and in the adjacent normal liver.

Original language	English
Pages (from-to)	143-151
Number of pages	9
Journal	Acta Hepatologica Japonica
Volume	54
Issue number	2
DOIs	https://doi.org/10.2957/kanzo.54.143
State	Published - 2013

Keywords

CD34
Coronal enhancement
Hepatic angiomyolipoma
Hepatocellular carcinoma
OATP

ASJC Scopus subject areas

Hepatology

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10.2957/kanzo.54.143

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Motoo, I., Takahara, T., Matsui, K., Kawabe, H., Kawai, K., Taziri, K., Tokimitsu, Y., Yasumura, S., Minemura, M., Miwa, S., Tsuneyama, K., Sugiyama, T., & Tsukada, K. (2013). Two cases of hepatic angiomyolipoma with difficulty for imaging differential diagnosis with hepatocellular carcinoma. Acta Hepatologica Japonica, 54(2), 143-151. https://doi.org/10.2957/kanzo.54.143

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title = "Two cases of hepatic angiomyolipoma with difficulty for imaging differential diagnosis with hepatocellular carcinoma",

abstract = "Casel was a 79-year-old male with liver tumor. Dynamic CT showed a high density lesion in early phase and low in equilibrant phase. Gd-EOB-DTPA-enhanced MRI showed a high intensitylesioninarterial phase and a low intensity lesion in hepatobiliary phase. US-guided biopsy led to histopathological diagnosis as hepatic an-giomyolipoma. Case2 was a 40-year-old with liver tumor. Dynamic CT showed a high density lesion in early phase, low with coronal enhancement in portal phase and low in equilibrant phase. Gd-EOB-DTPA-enhanced MRI showed a high intensity area in arterial phase, low with coronal enhancement in portal phase and low in hepatobiliary phase. Both CT and MRI showed peritumoral coronal enhancement in portal phase. Histological diagnosis ofla-paroscopic surgery was hepatic angiomyolipoma. Immunohistochemical examination showed OATP was negative in the tumor but the cellular membranes of adjacent normal hepatocytes were positive. We also detected immunostaining of CD34 in the dilated vessels in fibrous capsule around the tumor and in the adjacent normal liver.",

keywords = "CD34, Coronal enhancement, Hepatic angiomyolipoma, Hepatocellular carcinoma, OATP",

author = "Iori Motoo and Terumi Takahara and Koushi Matsui and Hideto Kawabe and Kengo Kawai and Kazuto Taziri and Yoshimitsu Tokimitsu and Satoshi Yasumura and Masami Minemura and Shigeharu Miwa and Koichi Tsuneyama and Toshiro Sugiyama and Kazuhiro Tsukada",

year = "2013",

doi = "10.2957/kanzo.54.143",

language = "英語",

volume = "54",

pages = "143--151",

journal = "Acta Hepatologica Japonica",

issn = "0451-4203",

publisher = "Japan Society of Hepatology",

number = "2",

}

Motoo, I, Takahara, T, Matsui, K, Kawabe, H, Kawai, K, Taziri, K, Tokimitsu, Y, Yasumura, S, Minemura, M, Miwa, S, Tsuneyama, K, Sugiyama, T & Tsukada, K 2013, 'Two cases of hepatic angiomyolipoma with difficulty for imaging differential diagnosis with hepatocellular carcinoma', Acta Hepatologica Japonica, vol. 54, no. 2, pp. 143-151. https://doi.org/10.2957/kanzo.54.143

TY - JOUR

T1 - Two cases of hepatic angiomyolipoma with difficulty for imaging differential diagnosis with hepatocellular carcinoma

AU - Motoo, Iori

AU - Takahara, Terumi

AU - Matsui, Koushi

AU - Kawabe, Hideto

AU - Kawai, Kengo

AU - Taziri, Kazuto

AU - Tokimitsu, Yoshimitsu

AU - Yasumura, Satoshi

AU - Minemura, Masami

AU - Miwa, Shigeharu

AU - Tsuneyama, Koichi

AU - Sugiyama, Toshiro

AU - Tsukada, Kazuhiro

PY - 2013

Y1 - 2013

N2 - Casel was a 79-year-old male with liver tumor. Dynamic CT showed a high density lesion in early phase and low in equilibrant phase. Gd-EOB-DTPA-enhanced MRI showed a high intensitylesioninarterial phase and a low intensity lesion in hepatobiliary phase. US-guided biopsy led to histopathological diagnosis as hepatic an-giomyolipoma. Case2 was a 40-year-old with liver tumor. Dynamic CT showed a high density lesion in early phase, low with coronal enhancement in portal phase and low in equilibrant phase. Gd-EOB-DTPA-enhanced MRI showed a high intensity area in arterial phase, low with coronal enhancement in portal phase and low in hepatobiliary phase. Both CT and MRI showed peritumoral coronal enhancement in portal phase. Histological diagnosis ofla-paroscopic surgery was hepatic angiomyolipoma. Immunohistochemical examination showed OATP was negative in the tumor but the cellular membranes of adjacent normal hepatocytes were positive. We also detected immunostaining of CD34 in the dilated vessels in fibrous capsule around the tumor and in the adjacent normal liver.

AB - Casel was a 79-year-old male with liver tumor. Dynamic CT showed a high density lesion in early phase and low in equilibrant phase. Gd-EOB-DTPA-enhanced MRI showed a high intensitylesioninarterial phase and a low intensity lesion in hepatobiliary phase. US-guided biopsy led to histopathological diagnosis as hepatic an-giomyolipoma. Case2 was a 40-year-old with liver tumor. Dynamic CT showed a high density lesion in early phase, low with coronal enhancement in portal phase and low in equilibrant phase. Gd-EOB-DTPA-enhanced MRI showed a high intensity area in arterial phase, low with coronal enhancement in portal phase and low in hepatobiliary phase. Both CT and MRI showed peritumoral coronal enhancement in portal phase. Histological diagnosis ofla-paroscopic surgery was hepatic angiomyolipoma. Immunohistochemical examination showed OATP was negative in the tumor but the cellular membranes of adjacent normal hepatocytes were positive. We also detected immunostaining of CD34 in the dilated vessels in fibrous capsule around the tumor and in the adjacent normal liver.

KW - CD34

KW - Coronal enhancement

KW - Hepatic angiomyolipoma

KW - Hepatocellular carcinoma

KW - OATP

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U2 - 10.2957/kanzo.54.143

DO - 10.2957/kanzo.54.143

M3 - 学術論文

AN - SCOPUS:84940338687

SN - 0451-4203

VL - 54

SP - 143

EP - 151

JO - Acta Hepatologica Japonica

JF - Acta Hepatologica Japonica

IS - 2

ER -

Two cases of hepatic angiomyolipoma with difficulty for imaging differential diagnosis with hepatocellular carcinoma

Abstract

Keywords

ASJC Scopus subject areas

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