Abstract
Transforming growth factor (TGF) beta and its superfamily, macrophage inhibitory cytokine (MIC) 1, are produced in adipose tissue. Adipocytes also produce thrombospondin (TSP) 1, an activator of TGF-beta1. TGF-beta regulates the gene expression related to the adipose tissue metabolism and plays an important role as an adipokine in the pathogenesis of many diseases.
| Original language | English |
|---|---|
| Title of host publication | Adipokines |
| Publisher | CRC Press |
| Pages | 128-134 |
| Number of pages | 7 |
| ISBN (Electronic) | 9781439879887 |
| ISBN (Print) | 9781138114418 |
| State | Published - 2016/04/19 |
ASJC Scopus subject areas
- General Medicine
- General Biochemistry, Genetics and Molecular Biology