Therapeutic applications of sugar-mimicking glycosidase inhibitors.

N. Asano*, A. Kato, A. A. Watson

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

67 Scopus citations

Abstract

Sugar-mimicking alkaloids inhibit the glycosidases involved in a wide range of important biological processes, principally owing to their structural resemblance to the sugar moiety of the natural substrate. The possibility of modifying and blocking these processes by using such inhibitors for therapeutic applications has attracted a lot of attention.

Original languageEnglish
Pages (from-to)145-154
Number of pages10
JournalMini reviews in medicinal chemistry
Volume1
Issue number2
DOIs
StatePublished - 2001/07

ASJC Scopus subject areas

  • Molecular Medicine
  • Pharmacology
  • Drug Discovery
  • Cancer Research

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