Potential role of orbitofrontal surface morphology on social and cognitive functions in high-risk subjects for psychosis and schizophrenia patients

Tsutomu Takahashi; Mihoko Nakamura; Yumiko Nishikawa; Yuko Komori; Shimako Nishiyama; Yoichiro Takayanagi; Atsushi Furuichi; Mikio Kido; Daiki Sasabayashi; Yuko Higuchi; Kyo Noguchi; Michio Suzuki

doi:10.1016/j.pscychresns.2018.12.002

Potential role of orbitofrontal surface morphology on social and cognitive functions in high-risk subjects for psychosis and schizophrenia patients

Tsutomu Takahashi^*, Mihoko Nakamura, Yumiko Nishikawa, Yuko Komori, Shimako Nishiyama, Yoichiro Takayanagi, Atsushi Furuichi, Mikio Kido, Daiki Sasabayashi, Yuko Higuchi, Kyo Noguchi, Michio Suzuki

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

This MRI study examined the surface morphology of the orbitofrontal cortex (OFC) and its relation to social and cognitive functions in 38 individuals with at-risk mental state (ARMS) and 63 schizophrenia patients in comparison with 61 healthy controls. The ARMS and schizophrenia groups had increased right OFC Type III expression and fewer orbital sulci, which were partly associated with social and cognitive impairments. OFC underdevelopment may underlie vulnerability to psychosis, as well as the core clinical features of the illness.

Original language	English
Pages (from-to)	92-95
Number of pages	4
Journal	Psychiatry Research - Neuroimaging
Volume	283
DOIs	https://doi.org/10.1016/j.pscychresns.2018.12.002
State	Published - 2019/01/30

Keywords

Cognition
Orbitofrontal cortex
Social function

ASJC Scopus subject areas

Neuroscience (miscellaneous)
Radiology Nuclear Medicine and imaging
Psychiatry and Mental health

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.pscychresns.2018.12.002

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Takahashi, T., Nakamura, M., Nishikawa, Y., Komori, Y., Nishiyama, S., Takayanagi, Y., Furuichi, A., Kido, M., Sasabayashi, D., Higuchi, Y., Noguchi, K., & Suzuki, M. (2019). Potential role of orbitofrontal surface morphology on social and cognitive functions in high-risk subjects for psychosis and schizophrenia patients. Psychiatry Research - Neuroimaging, 283, 92-95. https://doi.org/10.1016/j.pscychresns.2018.12.002

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abstract = "This MRI study examined the surface morphology of the orbitofrontal cortex (OFC) and its relation to social and cognitive functions in 38 individuals with at-risk mental state (ARMS) and 63 schizophrenia patients in comparison with 61 healthy controls. The ARMS and schizophrenia groups had increased right OFC Type III expression and fewer orbital sulci, which were partly associated with social and cognitive impairments. OFC underdevelopment may underlie vulnerability to psychosis, as well as the core clinical features of the illness.",

keywords = "Cognition, Orbitofrontal cortex, Social function",

author = "Tsutomu Takahashi and Mihoko Nakamura and Yumiko Nishikawa and Yuko Komori and Shimako Nishiyama and Yoichiro Takayanagi and Atsushi Furuichi and Mikio Kido and Daiki Sasabayashi and Yuko Higuchi and Kyo Noguchi and Michio Suzuki",

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doi = "10.1016/j.pscychresns.2018.12.002",

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Takahashi, T, Nakamura, M, Nishikawa, Y, Komori, Y, Nishiyama, S, Takayanagi, Y, Furuichi, A, Kido, M, Sasabayashi, D , Higuchi, Y , Noguchi, K & Suzuki, M 2019, 'Potential role of orbitofrontal surface morphology on social and cognitive functions in high-risk subjects for psychosis and schizophrenia patients', Psychiatry Research - Neuroimaging, vol. 283, pp. 92-95. https://doi.org/10.1016/j.pscychresns.2018.12.002

TY - JOUR

T1 - Potential role of orbitofrontal surface morphology on social and cognitive functions in high-risk subjects for psychosis and schizophrenia patients

AU - Takahashi, Tsutomu

AU - Nakamura, Mihoko

AU - Nishikawa, Yumiko

AU - Komori, Yuko

AU - Nishiyama, Shimako

AU - Takayanagi, Yoichiro

AU - Furuichi, Atsushi

AU - Kido, Mikio

AU - Sasabayashi, Daiki

AU - Higuchi, Yuko

AU - Noguchi, Kyo

AU - Suzuki, Michio

PY - 2019/1/30

Y1 - 2019/1/30

N2 - This MRI study examined the surface morphology of the orbitofrontal cortex (OFC) and its relation to social and cognitive functions in 38 individuals with at-risk mental state (ARMS) and 63 schizophrenia patients in comparison with 61 healthy controls. The ARMS and schizophrenia groups had increased right OFC Type III expression and fewer orbital sulci, which were partly associated with social and cognitive impairments. OFC underdevelopment may underlie vulnerability to psychosis, as well as the core clinical features of the illness.

AB - This MRI study examined the surface morphology of the orbitofrontal cortex (OFC) and its relation to social and cognitive functions in 38 individuals with at-risk mental state (ARMS) and 63 schizophrenia patients in comparison with 61 healthy controls. The ARMS and schizophrenia groups had increased right OFC Type III expression and fewer orbital sulci, which were partly associated with social and cognitive impairments. OFC underdevelopment may underlie vulnerability to psychosis, as well as the core clinical features of the illness.

KW - Cognition

KW - Orbitofrontal cortex

KW - Social function

UR - http://www.scopus.com/inward/record.url?scp=85058577577&partnerID=8YFLogxK

U2 - 10.1016/j.pscychresns.2018.12.002

DO - 10.1016/j.pscychresns.2018.12.002

M3 - 学術論文

C2 - 30576941

AN - SCOPUS:85058577577

SN - 0925-4927

VL - 283

SP - 92

EP - 95

JO - Psychiatry Research - Neuroimaging

JF - Psychiatry Research - Neuroimaging

ER -

Potential role of orbitofrontal surface morphology on social and cognitive functions in high-risk subjects for psychosis and schizophrenia patients

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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