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Optical absorption measurement of biological tissues using ultrasound-induced light deflection

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

A measurement method based on ultrasound-induced light deflection is proposed for localized optical absorption characterization in biological tissues. In this method, a focused laser beam is incident perpendicular to the direction of ultrasound pulse propagation. By measuring the transmitted light intensity, temporal variations due to light deflection are detected. Since the measured waveform reflects the absorption characteristics around the laser light spot, localized absorption properties can be determined through computational analysis. We discussed the measurement principle using the Monte-Carlo simulations. The ultrasound pulse in the medium was modeled as a dielectric slab waveguides with graded index profile. Simulations with a virtual blood vessel phantom showed the highest sensitivity at a 1 mm depth under the skin.

Original languageEnglish
Title of host publicationPhotons Plus Ultrasound
Subtitle of host publicationImaging and Sensing 2025
EditorsAlexander A. Oraevsky, Lihong V. Wang
PublisherSPIE
ISBN (Electronic)9781510683860
DOIs
StatePublished - 2025
EventPhotons Plus Ultrasound: Imaging and Sensing 2025 - San Francisco, United States
Duration: 2025/01/262025/01/29

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume13319
ISSN (Print)1605-7422

Conference

ConferencePhotons Plus Ultrasound: Imaging and Sensing 2025
Country/TerritoryUnited States
CitySan Francisco
Period2025/01/262025/01/29

Keywords

  • Monte Carlo simulation
  • optical absorption spectroscopy
  • ultrasound-induced light deflection

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

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