Open-label study of cognitive behavioural therapy for individuals with at-risk mental state: Feasibility in the Japanese clinical setting

Kazunori Matsumoto; Noriyuki Ohmuro; Naohisa Tsujino; Shimako Nishiyama; Koichi Abe; Yumiko Hamaie; Masahiro Katsura; Naomi Inoue; Hiroo Matsuoka; Yasuhiro Kawasaki; Toshifumi Kishimoto; Michio Suzuki; Masafumi Mizuno

doi:10.1111/eip.12541

Open-label study of cognitive behavioural therapy for individuals with at-risk mental state: Feasibility in the Japanese clinical setting

Kazunori Matsumoto^*, Noriyuki Ohmuro, Naohisa Tsujino, Shimako Nishiyama, Koichi Abe, Yumiko Hamaie, Masahiro Katsura, Naomi Inoue, Hiroo Matsuoka, Yasuhiro Kawasaki, Toshifumi Kishimoto, Michio Suzuki, Masafumi Mizuno

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Aim: To date, most cognitive behavioural therapy (CBT) trials for individuals with at-risk metal state (ARMS) have been conducted in few Western countries and its feasibility in other regions, including Japan, has not been established. Methods: We designed an open-label pilot study. Fourteen ARMS participants received CBT over 6 months and were followed-up for 6 months. Results: Thirteen individuals completed the CBT intervention and assessments. The mean total score on the Positive and Negative Syndrome Scale improved from 60.2 to 46.0 after the intervention (Cohen's d = 1.1). The effects were maintained at the follow-up assessment. One participant transitioned to psychosis after the CBT intervention, and was the only patient who received antipsychotics. Conclusions: We confirmed the feasibility of the provision of CBT for ARMS in Japan. Since overprescription of antipsychotics is a matter of great concern in Japan, CBT could be a valuable alternative treatment strategy.

Original language	English
Pages (from-to)	137-141
Number of pages	5
Journal	Early Intervention in Psychiatry
Volume	13
Issue number	1
DOIs	https://doi.org/10.1111/eip.12541
State	Published - 2019/02

Keywords

at-risk mental state
cognitive behavioural therapy
early intervention
psychological treatment
psychosis

ASJC Scopus subject areas

Psychiatric Mental Health
Psychiatry and Mental health
Biological Psychiatry

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1111/eip.12541

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Matsumoto, K., Ohmuro, N., Tsujino, N., Nishiyama, S., Abe, K., Hamaie, Y., Katsura, M., Inoue, N., Matsuoka, H., Kawasaki, Y., Kishimoto, T., Suzuki, M., & Mizuno, M. (2019). Open-label study of cognitive behavioural therapy for individuals with at-risk mental state: Feasibility in the Japanese clinical setting. Early Intervention in Psychiatry, 13(1), 137-141. https://doi.org/10.1111/eip.12541

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title = "Open-label study of cognitive behavioural therapy for individuals with at-risk mental state: Feasibility in the Japanese clinical setting",

abstract = "Aim: To date, most cognitive behavioural therapy (CBT) trials for individuals with at-risk metal state (ARMS) have been conducted in few Western countries and its feasibility in other regions, including Japan, has not been established. Methods: We designed an open-label pilot study. Fourteen ARMS participants received CBT over 6 months and were followed-up for 6 months. Results: Thirteen individuals completed the CBT intervention and assessments. The mean total score on the Positive and Negative Syndrome Scale improved from 60.2 to 46.0 after the intervention (Cohen's d = 1.1). The effects were maintained at the follow-up assessment. One participant transitioned to psychosis after the CBT intervention, and was the only patient who received antipsychotics. Conclusions: We confirmed the feasibility of the provision of CBT for ARMS in Japan. Since overprescription of antipsychotics is a matter of great concern in Japan, CBT could be a valuable alternative treatment strategy.",

keywords = "at-risk mental state, cognitive behavioural therapy, early intervention, psychological treatment, psychosis",

author = "Kazunori Matsumoto and Noriyuki Ohmuro and Naohisa Tsujino and Shimako Nishiyama and Koichi Abe and Yumiko Hamaie and Masahiro Katsura and Naomi Inoue and Hiroo Matsuoka and Yasuhiro Kawasaki and Toshifumi Kishimoto and Michio Suzuki and Masafumi Mizuno",

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year = "2019",

month = feb,

doi = "10.1111/eip.12541",

language = "英語",

volume = "13",

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Matsumoto, K, Ohmuro, N, Tsujino, N, Nishiyama, S, Abe, K, Hamaie, Y, Katsura, M, Inoue, N, Matsuoka, H, Kawasaki, Y, Kishimoto, T, Suzuki, M & Mizuno, M 2019, 'Open-label study of cognitive behavioural therapy for individuals with at-risk mental state: Feasibility in the Japanese clinical setting', Early Intervention in Psychiatry, vol. 13, no. 1, pp. 137-141. https://doi.org/10.1111/eip.12541

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T1 - Open-label study of cognitive behavioural therapy for individuals with at-risk mental state

T2 - Feasibility in the Japanese clinical setting

AU - Matsumoto, Kazunori

AU - Ohmuro, Noriyuki

AU - Tsujino, Naohisa

AU - Nishiyama, Shimako

AU - Abe, Koichi

AU - Hamaie, Yumiko

AU - Katsura, Masahiro

AU - Inoue, Naomi

AU - Matsuoka, Hiroo

AU - Kawasaki, Yasuhiro

AU - Kishimoto, Toshifumi

AU - Suzuki, Michio

AU - Mizuno, Masafumi

PY - 2019/2

Y1 - 2019/2

N2 - Aim: To date, most cognitive behavioural therapy (CBT) trials for individuals with at-risk metal state (ARMS) have been conducted in few Western countries and its feasibility in other regions, including Japan, has not been established. Methods: We designed an open-label pilot study. Fourteen ARMS participants received CBT over 6 months and were followed-up for 6 months. Results: Thirteen individuals completed the CBT intervention and assessments. The mean total score on the Positive and Negative Syndrome Scale improved from 60.2 to 46.0 after the intervention (Cohen's d = 1.1). The effects were maintained at the follow-up assessment. One participant transitioned to psychosis after the CBT intervention, and was the only patient who received antipsychotics. Conclusions: We confirmed the feasibility of the provision of CBT for ARMS in Japan. Since overprescription of antipsychotics is a matter of great concern in Japan, CBT could be a valuable alternative treatment strategy.

AB - Aim: To date, most cognitive behavioural therapy (CBT) trials for individuals with at-risk metal state (ARMS) have been conducted in few Western countries and its feasibility in other regions, including Japan, has not been established. Methods: We designed an open-label pilot study. Fourteen ARMS participants received CBT over 6 months and were followed-up for 6 months. Results: Thirteen individuals completed the CBT intervention and assessments. The mean total score on the Positive and Negative Syndrome Scale improved from 60.2 to 46.0 after the intervention (Cohen's d = 1.1). The effects were maintained at the follow-up assessment. One participant transitioned to psychosis after the CBT intervention, and was the only patient who received antipsychotics. Conclusions: We confirmed the feasibility of the provision of CBT for ARMS in Japan. Since overprescription of antipsychotics is a matter of great concern in Japan, CBT could be a valuable alternative treatment strategy.

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Open-label study of cognitive behavioural therapy for individuals with at-risk mental state: Feasibility in the Japanese clinical setting

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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