[Establishment of the rapid, hypersensitive testing systems for sepsis/SIRS].

Isao Kitajima*, Hideki Niimi

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

3 Scopus citations

Abstract

We developed a new infectious disease diagnostic system in order to raise the lifesaving rate in systemic inflammatory reactive syndrome, SIRS. Using eukaryote-derived thermostable DNA polymerase, the sensitive and reliable detection of bacteria becomes feasible for large fields, thereby making the development of a wide range of powerful applications possible. Further, we have established a novel measurement system for NF-kappaB activity using fluorescence correlation spectroscopy(FCS) because the elevation of NF-kappaB activity reflects acute inflammation. NF-kappaB activity measurement in patients with SIRS may provide a useful inflammatory marker.

Original languageEnglish
Pages (from-to)46-51
Number of pages6
JournalRinsho byori. The Japanese journal of clinical pathology
Volume60
Issue number1
StatePublished - 2012/01

ASJC Scopus subject areas

  • General Medicine

Fingerprint

Dive into the research topics of '[Establishment of the rapid, hypersensitive testing systems for sepsis/SIRS].'. Together they form a unique fingerprint.

Cite this