Enantiomeric C-6 fluorinated swainsonine derivatives as highly selective and potent inhibitors of α-mannosidase and α-L-rhamnosidase: Design, synthesis and structure-activity relationship study

Feng-Teng Gao; Ming Zhang; Yuna Shimadate; Atsushi Kato; Yi-Xian Li; Yue-Mei Jia; Chu-Yi Yu

doi:10.1016/j.ejmech.2024.117031

Enantiomeric C-6 fluorinated swainsonine derivatives as highly selective and potent inhibitors of α-mannosidase and α-L-rhamnosidase: Design, synthesis and structure-activity relationship study

Feng-Teng Gao, Ming Zhang, Yuna Shimadate, Atsushi Kato, Yi-Xian Li, Yue-Mei Jia, Chu-Yi Yu

Hospital Pharmacy

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	117031
Journal	European Journal of Medicinal Chemistry
Volume	282
DOIs	https://doi.org/10.1016/j.ejmech.2024.117031
State	Published - 2025/01/01

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10.1016/j.ejmech.2024.117031

https://linkinghub.elsevier.com/retrieve/pii/S0223523424009139

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Gao, F.-T., Zhang, M., Shimadate, Y., Kato, A., Li, Y.-X., Jia, Y.-M., & Yu, C.-Y. (2025). Enantiomeric C-6 fluorinated swainsonine derivatives as highly selective and potent inhibitors of α-mannosidase and α-L-rhamnosidase: Design, synthesis and structure-activity relationship study. European Journal of Medicinal Chemistry, 282, 117031. https://doi.org/10.1016/j.ejmech.2024.117031

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title = "Enantiomeric C-6 fluorinated swainsonine derivatives as highly selective and potent inhibitors of α-mannosidase and α-L-rhamnosidase: Design, synthesis and structure-activity relationship study",

author = "Feng-Teng Gao and Ming Zhang and Yuna Shimadate and Atsushi Kato and Yi-Xian Li and Yue-Mei Jia and Chu-Yi Yu",

year = "2025",

month = jan,

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language = "英語",

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Gao, F-T, Zhang, M, Shimadate, Y, Kato, A, Li, Y-X, Jia, Y-M & Yu, C-Y 2025, 'Enantiomeric C-6 fluorinated swainsonine derivatives as highly selective and potent inhibitors of α-mannosidase and α-L-rhamnosidase: Design, synthesis and structure-activity relationship study', European Journal of Medicinal Chemistry, vol. 282, pp. 117031. https://doi.org/10.1016/j.ejmech.2024.117031

Enantiomeric C-6 fluorinated swainsonine derivatives as highly selective and potent inhibitors of α-mannosidase and α-L-rhamnosidase: Design, synthesis and structure-activity relationship study. / Gao, Feng-Teng; Zhang, Ming; Shimadate, Yuna et al.
In: European Journal of Medicinal Chemistry, Vol. 282, 01.01.2025, p. 117031.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Enantiomeric C-6 fluorinated swainsonine derivatives as highly selective and potent inhibitors of α-mannosidase and α-L-rhamnosidase: Design, synthesis and structure-activity relationship study

AU - Gao, Feng-Teng

AU - Zhang, Ming

AU - Shimadate, Yuna

AU - Kato, Atsushi

AU - Li, Yi-Xian

AU - Jia, Yue-Mei

AU - Yu, Chu-Yi

PY - 2025/1/1

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DO - 10.1016/j.ejmech.2024.117031

M3 - 学術論文

C2 - 39556895

SN - 0223-5234

VL - 282

SP - 117031

JO - European Journal of Medicinal Chemistry

JF - European Journal of Medicinal Chemistry

ER -