Effects of propofol and thiamylal on swallowing reflex

M. Sakamaki*, A. Masuda, K. Hirota, Y. Ito

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

We investigated the effects of propofol and thiamylal on swallowing reflex in 26 adult volunteers. They were sedated with either propofol (Group P: n = 16) or thiamylal (Group T: n = 10). Swallowing was induced by bolus rejections of distilled water (0.25, 0.5, 0.75 and 1.0 mL) into the pharynx via an epidural catheter. The responses to injections of water were analyzed in terms of the number of swallows elicited and the latency of response. The latency was prolonged and the number of swallows were decreased in Group P, but not in Group T. These results suggest that propofol depresses swallowing reflex greater than that of thiamylal.

Original languageEnglish
Pages (from-to)11-14
Number of pages4
JournalHokuriku Journal of Anesthesiology
Volume32
Issue number1
StatePublished - 1998

Keywords

  • Propofol
  • Swallowing reflex
  • Thiamylal

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

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