Effects of general anesthetics on excitatory and inhibitory synaptic pathways of hippocampus in vitro

K. Hirota; R. Sasaki; T. Asahi; M. Yamazaki

doi:10.1016/j.ics.2005.07.021

Effects of general anesthetics on excitatory and inhibitory synaptic pathways of hippocampus in vitro

K. Hirota^*, R. Sasaki, T. Asahi, M. Yamazaki

^*Corresponding author for this work

Anesthesiology

Research output: Contribution to journal › Article › peer-review

Abstract

We studied the effects of intravenous and volatile anesthetics on evoked-field potentials using bi- and tri-synaptic pathways of rat hippocampal slices in vitro. The results predict that three to six synapses may be involved to generate synaptic modulation with clinical concentrations of general anesthetics.

Original language	English
Pages (from-to)	195-198
Number of pages	4
Journal	International Congress Series
Volume	1283
DOIs	https://doi.org/10.1016/j.ics.2005.07.021
State	Published - 2005/11

Keywords

General anesthetics
Hippocampus
Neural networks
Synaptic transmission

ASJC Scopus subject areas

General Medicine

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10.1016/j.ics.2005.07.021

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title = "Effects of general anesthetics on excitatory and inhibitory synaptic pathways of hippocampus in vitro",

abstract = "We studied the effects of intravenous and volatile anesthetics on evoked-field potentials using bi- and tri-synaptic pathways of rat hippocampal slices in vitro. The results predict that three to six synapses may be involved to generate synaptic modulation with clinical concentrations of general anesthetics.",

keywords = "General anesthetics, Hippocampus, Neural networks, Synaptic transmission",

author = "K. Hirota and R. Sasaki and T. Asahi and M. Yamazaki",

year = "2005",

month = nov,

doi = "10.1016/j.ics.2005.07.021",

language = "英語",

volume = "1283",

pages = "195--198",

journal = "International Congress Series",

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T1 - Effects of general anesthetics on excitatory and inhibitory synaptic pathways of hippocampus in vitro

AU - Hirota, K.

AU - Sasaki, R.

AU - Asahi, T.

AU - Yamazaki, M.

PY - 2005/11

Y1 - 2005/11

N2 - We studied the effects of intravenous and volatile anesthetics on evoked-field potentials using bi- and tri-synaptic pathways of rat hippocampal slices in vitro. The results predict that three to six synapses may be involved to generate synaptic modulation with clinical concentrations of general anesthetics.

AB - We studied the effects of intravenous and volatile anesthetics on evoked-field potentials using bi- and tri-synaptic pathways of rat hippocampal slices in vitro. The results predict that three to six synapses may be involved to generate synaptic modulation with clinical concentrations of general anesthetics.

KW - General anesthetics

KW - Hippocampus

KW - Neural networks

KW - Synaptic transmission

UR - http://www.scopus.com/inward/record.url?scp=33646461567&partnerID=8YFLogxK

U2 - 10.1016/j.ics.2005.07.021

DO - 10.1016/j.ics.2005.07.021

M3 - 学術論文

AN - SCOPUS:33646461567

SN - 0531-5131

VL - 1283

SP - 195

EP - 198

JO - International Congress Series

JF - International Congress Series

ER -

Effects of general anesthetics on excitatory and inhibitory synaptic pathways of hippocampus in vitro

Abstract

Keywords

ASJC Scopus subject areas

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