Differential actions of volatile and intravenous anesthetics on recurrent inhibitory interneurons in rat hippocampal slices

Takehisa Asahi*, Koki Hirota, Rika Sasaki, Yamazaki Mitsuaki

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

We examined the effects of both volatile and intravenous general anesthetics (GAs) on excitatory synaptic transmission with and without recurrent inhibition in CA1 neurons in rat hippocampal slice. Volatile anesthetics (VAs) act mainly on excitatory pathways, whereas intravenous anesthetics (IAs) alter mainly recurrent inhibitory pathways.

Original languageEnglish
Pages (from-to)304-305
Number of pages2
JournalInternational Congress Series
Volume1283
DOIs
StatePublished - 2005/11

Keywords

  • CA1
  • General anesthetics
  • Recurrent inhibition

ASJC Scopus subject areas

  • General Medicine

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