Abstract
The terpene core structure of suaveolindoles was synthesized through a concise route in a time-economical manner. A scalable synthetic route from pulegone delivered the desired α, β, γ, unsaturated ester in a brief period. By way of Eschenmoser Claisen rearrangement, carbon side-chain moiety at the crowded double-allylic position was introduced stereoselectively.
Original language | English |
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Article number | st-2021-l0423-l |
Pages (from-to) | 273-276 |
Number of pages | 4 |
Journal | Synlett |
Volume | 33 |
Issue number | 3 |
DOIs | |
State | Published - 2022/02 |
Keywords
- Claisen rearrangement
- DFT calculation
- natural product synthesis
- terpene
- time-economy synthesis
ASJC Scopus subject areas
- Organic Chemistry