Abstract
Background/Aim: Bone and soft-tissue sarcomas of the head and neck have very poor prognoses. This prospective study aimed to investigate the efficacy and safety of carbon-ion radiotherapy (C-ion RT) for bone and softtissue sarcoma of the head and neck. Patients and Methods: The present study was a prospective clinical study that included 10 consecutive patients diagnosed with bone and soft-tissue sarcoma of the head and neck who were treated with C-ion RT between 2012 and 2018 at our institution. CIon RT consisted of 70.4 Gy (relative biological effectiveness) in 16 fractions. Results: The 3-year local control, overall survival, and progression-free survival rates for patients overall were 72.9%, 77.8%, and 36%, respectively. Conclusion: The present study demonstrated the efficacy of C-ion RT for bone and soft-tissue sarcoma of the head and neck; adverse events were within the expected range.
| Original language | English |
|---|---|
| Pages (from-to) | 1439-1446 |
| Number of pages | 8 |
| Journal | Anticancer Research |
| Volume | 42 |
| Issue number | 3 |
| DOIs | |
| State | Published - 2022/03 |
Keywords
- Bone and soft-tissue sarcoma
- Carbon-ion radiotherapy
- Head and neck tumor
ASJC Scopus subject areas
- Oncology
- Cancer Research