Abstract
Organic azide cyclization reactions with 1- Aryl allylic alcohols were investigated in a synthetic study of phenanthroindolizidine alkaloids. Unsaturated imines (enimines) were effectively obtained from the allylic alcohol adjacent to electron-rich aromatic rings under thermal reaction conditions. The tandem aziridination-Nazarov reactions to indenyl aziridines were preferred to the acid-mediated enimine formation via Schmidt reaction in the case of 3- Aryl diallylic alcohols.
Original language | English |
---|---|
Pages (from-to) | 1313-1327 |
Number of pages | 15 |
Journal | Heterocycles |
Volume | 92 |
Issue number | 7 |
DOIs | |
State | Published - 2016 |
ASJC Scopus subject areas
- Analytical Chemistry
- Pharmacology
- Organic Chemistry