Projects per year
Personal profile
Campus career
機能性分子創成変換システム学系 助教 2019/04/01-2019/09/30
工学系 助教 2019/10/01-
工学科 助教 2019/10/01-
工学部工学科 基幹教員
学部運営への参画状況・・・有-教授会
担当授業科目に係る状況・・・主要授業科目担当
Affiliated academic society
日本薬学会
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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Rejuvenation of Oocytes through a Fundamental Understanding of Aging
Koike, S. (Principal Investigator), Nakashima, A. (Co-Investigator(Kenkyū-buntansha)), Oshima, Y. (Co-Investigator(Kenkyū-buntansha)) & Okada, T. (Co-Investigator(Kenkyū-buntansha))
Japan Society for the Promotion of Science
2025/04/01 → 2028/03/31
Project: Research Project
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中性子解析に基づく分子標的薬の選択性向上と治療薬開発
Yokoyama, T. (Principal Investigator) & Okada, T. (Co-Investigator(Kenkyū-buntansha))
Japan Society for the Promotion of Science
2024/04/01 → 2027/03/31
Project: Research Project
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Synthetic studies on broussonetine N aimed at creating novel glycosidase inhibitors
Okada, T. (PI)
2019/08/30 → 2021/03/31
Project: Research
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Rapid and long-lasting antidepressant-like effects of the pituitary adenylate cyclase-activating polypeptide receptor antagonist PA-915 in chronic stress mouse models
Shintani, Y., Hayata-Takano, A., Takasaki, I., Kurihara, T., Miyata, A., Yamano, Y., Ikuta, M., Takeshita, R., Murata, K., Oguri, T., Asaka, C., Nunomura, K., Lin, B., Nakagawa, S., Okada, T., Toyooka, N., Takumi, T., Ago, Y., Takuma, K. & Hashimoto, H., 2026/02, In: Molecular Psychiatry. 31, 2, p. 1014-1026 13 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Acute toxicity of frog-skin-homologous synthetic alkaloids and frog-skin extracts: miniaturized test to evaluate toxicity with Daphnia magna
Méndez-Rivera, M., Ramírez-Morales, D., Mora-Machado, A., Pröhl, H., Rodríguez, A., Victor, V. C., Vasiliki, M. O., Okada, T., Toyooka, N., Ibáñez, R., Rodríguez-Rodríguez, C. E. & Tamayo-Castillo, G., 2025/12, In: Toxicon. 268, 108599.Research output: Contribution to journal › Article › peer-review
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Construction of trans-2,6-Disubstituted Piperidine Skeleton and Its Application to the Total Synthesis of (−)-Myrtine and trans-Piperidine-Type Poison-Frog Alkaloids
Okada, T., Eguchi, K., Hasegawa, F., Ikhlaq, M. M., Yoshikawa, T. & Toyooka, N., 2025/02/21, In: Journal of Organic Chemistry. 90, 7, p. 2749-2759 11 p.Research output: Contribution to journal › Article › peer-review
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Design of specific autophagy inhibitors for use as anti-cancer drug
Kobayashi, N., Ogino, M., Kudo, Y., Yoshino, Y., Ikari, A., Okada, T., Endo, S. & Toyooka, N., 2025.Research output: Contribution to conference › Presentation
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Discovery and Structural Optimization of a Novel Serine Racemase Inhibitor with a Pyridazine Skeleton
Tozawa, C., Matsukiyo, Y., Oshima, S., Sakajiri, Y., Maeda, C., Shibata, T., Sawada, R., Okada, T., Obita, T., Mizuguchi, M., Mori, H., Yamanishi, Y. & Toyooka, N., 2025/10/06, In: ChemistrySelect. 10, 37, e05651.Research output: Contribution to journal › Article › peer-review
Datasets
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Crystal structure of V30M mutated transthyretin in complex with 4-chloro-9-oxo-9H-xanthene-2-carboxylic acid
Kitakami, R. (Contributor), Inui, K. (Contributor), Nakagawa, Y. (Contributor), Sawai, Y. (Contributor), Katayama, W. (Contributor), Yokoyama, T. (Contributor), Okada, T. (Contributor), Kanamitsu, K. (Contributor), Nakagawa, S. (Contributor), Toyooka, N. (Contributor) & Mizuguchi, M. (Contributor), Protein Data Bank (PDB), 2021/10/13
DOI: 10.2210/pdb7DT8/pdb, https://www.wwpdb.org/pdb?id=pdb_00007dt8
Dataset
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Crystal structure of V30M-TTR in complex with naringenin derivative-18
Mizuguchi, M. (Contributor), Nakagawa, Y. (Contributor), Inui, K. (Contributor), Katayama, W. (Contributor), Sawai, Y. (Contributor), Shimane, A. (Contributor), Kitakami, R. (Contributor), Okada, T. (Contributor), Nabeshima, Y. (Contributor), Yokoyama, T. (Contributor), Kanamitsu, K. (Contributor), Nakagawa, S. (Contributor) & Toyooka, N. (Contributor), Protein Data Bank (PDB), 2022/12/14
DOI: 10.2210/pdb7W9R/pdb, https://www.wwpdb.org/pdb?id=pdb_00007w9r
Dataset
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Crystal structures of AKR1C3 binary complex with NADP+
Endo, S. (Contributor), Oguri, H. (Contributor), Segawa, J. (Contributor), Kawai, M. (Contributor), Hu, D. (Contributor), Xia, S. (Contributor), Okada, T. (Contributor), Irie, K. (Contributor), Fujii, S. (Contributor), Gouda, H. (Contributor), Iguchi, K. (Contributor), Matsukawa, T. (Contributor), Fujimoto, N. (Contributor), Nakayama, T. (Contributor), Toyooka, N. (Contributor), Matsunaga, T. (Contributor) & Ikari, A. (Contributor), Protein Data Bank (PDB), 2020/09/23
DOI: 10.2210/pdb7C7F/pdb, https://www.wwpdb.org/pdb?id=pdb_00007c7f
Dataset
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Crystal structures of AKR1C3 ternary complex with NADP+ and the chromene derivative 2l
Endo, S. (Contributor), Oguri, H. (Contributor), Segawa, J. (Contributor), Kawai, M. (Contributor), Hu, D. (Contributor), Xia, S. (Contributor), Okada, T. (Contributor), Irie, K. (Contributor), Fujii, S. (Contributor), Gouda, H. (Contributor), Iguchi, K. (Contributor), Matsukawa, T. (Contributor), Fujimoto, N. (Contributor), Nakayama, T. (Contributor), Toyooka, N. (Contributor), Matsunaga, T. (Contributor) & Ikari, A. (Contributor), Protein Data Bank (PDB), 2020/09/23
DOI: 10.2210/pdb7C7H/pdb, https://www.wwpdb.org/pdb?id=pdb_00007c7h
Dataset
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Crystal structure of V30M mutated transthyretin in complex with purpurin
Kitakami, R. (Contributor), Inui, K. (Contributor), Nakagawa, Y. (Contributor), Sawai, Y. (Contributor), Katayama, W. (Contributor), Yokoyama, T. (Contributor), Okada, T. (Contributor), Kanamitsu, K. (Contributor), Nakagawa, S. (Contributor), Toyooka, N. (Contributor) & Mizuguchi, M. (Contributor), Protein Data Bank (PDB), 2021/10/13
DOI: 10.2210/pdb7DT6/pdb, https://www.wwpdb.org/pdb?id=pdb_00007dt6
Dataset
Activities
- 74 Oral presentation
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Divergent Synthesis of PTX- and DHQ-type Poison-frog Alkaloids
Okada, T. (Speaker)
2022/11Activity: Talk or presentation › Oral presentation
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次世代型膵臓がん治療薬の開発研究 ―新規pipernonaline誘導体の合成および活性評価―
Okada, T. (Speaker)
2022/10Activity: Talk or presentation › Oral presentation
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2,6-trans-ピペリジン骨格構築法の開発と天然物合成への応用
Okada, T. (Speaker)
2022/10Activity: Talk or presentation › Oral presentation
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未病に焦点を当てた創薬:GLS1阻害に基づく新規抗肥満薬の開発研究
Okada, T. (Speaker)
2022/10Activity: Talk or presentation › Oral presentation
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トリプルネガティブ乳がん治療薬の開発を目指した新規DHRS11阻害剤の合成と活性評価
Okada, T. (Speaker)
2022/10Activity: Talk or presentation › Oral presentation