Projects per year
Personal profile
Campus career
機能性分子創成変換システム学系 助教 2019/04/01-2019/09/30
工学系 助教 2019/10/01-
工学科 助教 2019/10/01-
工学部工学科 基幹教員
学部運営への参画状況・・・有-教授会
担当授業科目に係る状況・・・主要授業科目担当
Affiliated academic society
日本薬学会
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
Projects
- 1 Finished
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Synthetic studies on broussonetine N aimed at creating novel glycosidase inhibitors
Okada, T. (PI)
2019/08/30 → 2021/03/31
Project: Research
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Development of Benziodarone Analogues with Enhanced Potency for Selective Binding to Transthyretin in Human Plasma
Mizuguchi, M., Nakagawa, Y., Yokoyama, T., Okada, T., Fujii, K., Takahashi, K., Luan, N. N. T., Nabeshima, Y., Kanamitsu, K., Nakagawa, S., Yamakawa, S., Ueda, M., Ando, Y. & Toyooka, N., 2024/05/09, In: Journal of Medicinal Chemistry. 67, 9, p. 6987-7005 19 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Divergent total synthesis of indolizidine-, quinolizidine-, and decahydroquinoline-type poison-frog alkaloids
Okada, T. & Toyooka, N., 2024/01, Advances in Heterocyclic Chemistry. Scriven, E. F. V. & Ramsden, C. A. (eds.). Academic Press Inc., p. 49-88 40 p. (Advances in Heterocyclic Chemistry; vol. 144).Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
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Synthesis of 8-epi-L-swainsonine, related C6 alkylated derivatives and their α-L-rhamnosidase inhibition
Shimadate, Y., Oshima, S., Kasamatsu, N., Yamamoto, S., Taguchi, A., Nash, R. J., Fleet, G. W. J., Okada, T., Toyooka, N. & Kato, A., 2024/03/01, In: Tetrahedron Letters. p. 155008Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Targeting Pancreatic Cancer with Novel Nicolaioidesin C Derivatives: Molecular Mechanism, In Vitro, and In Vivo Evaluations
Yamazaki, T., Phan, N. D., Maneenet, J., Yamagishi, M., Nishikawa, Y., Okada, T., Okumura, T., Toyooka, N., Fujii, T. & Awale, S., 2024/08/22, In: Journal of Medicinal Chemistry. 67, 16, p. 14313-14328 16 p.Research output: Contribution to journal › Article › peer-review
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Benziodarone and 6-hydroxybenziodarone are potent and selective inhibitors of transthyretin amyloidogenesis
Mizuguchi, M., Yokoyama, T., Okada, T., Nakagawa, Y., Fujii, K., Nabeshima, Y. & Toyooka, N., 2023/07/15, In: Bioorganic and Medicinal Chemistry. 90, 117370.Research output: Contribution to journal › Article › peer-review
5 Scopus citations
Activities
- 74 Oral presentation
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Divergent Synthesis of PTX- and DHQ-type Poison-frog Alkaloids
Okada, T. (Speaker)
2022/11Activity: Talk or presentation › Oral presentation
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次世代型膵臓がん治療薬の開発研究 ―新規pipernonaline誘導体の合成および活性評価―
Okada, T. (Speaker)
2022/10Activity: Talk or presentation › Oral presentation
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未病に焦点を当てた創薬:GLS1阻害に基づく新規抗肥満薬の開発研究
Okada, T. (Speaker)
2022/10Activity: Talk or presentation › Oral presentation
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核内受容体Nr4a1を標的とした新規抗がん鎮痛薬の開発研究
Okada, T. (Speaker)
2022/10Activity: Talk or presentation › Oral presentation
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トリプルネガティブ乳がん治療薬の開発を目指した新規DHRS11阻害剤の合成と活性評価
Okada, T. (Speaker)
2022/10Activity: Talk or presentation › Oral presentation