Calculated based on number of publications stored in Pure and citations from Scopus
20002024

Research activity per year

Personal profile

Research biography

The major focus of my research is directed toward the discovery of an "anti-austerity strategy" based on anticancer agents. These agents are useful for the treatment of pancreatic cancer, for which there is no reliable treatment at present. Pancreatic cancers are clinically hypovascular and have inherent tolerance to nutrition starvation. Elimination of this tolerance is a new "Antiausterity strategy" in anticancer drug discovery. Visit the following page for the details. http://nddlab.weebly.com

Laboratory Info

Laboratory Info

For Prospective Graduate Students
We welcome motivated students who wish to pursue careers in natural product chemistry, drug discovery, and drug development. State-of-the-art facilities are available in our lab to conduct advanced research in natural product chemistry, chemical biology, and molecular biology. Each researcher will master the art of isolation and identification of bioactive natural compounds, structure elucidation using the most advanced computer-assisted Nuclear Magnetic Resonance (NMR) spectroscopy technologies, and advanced computational calculations (ECD and NMR). Our laboratory has established a unique NMR strategy based on a chemical biology approach to understand the underlying mechanisms of cancer cells, metabolomes, drug actions, and biomarker discovery. In addition, we investigate the mechanism of action of anticancer drugs against cell survival pathways, with particular emphasis on the PI3K/Akt/mTOR/autophagy pathways.  

Our lab has extensive cross-disciplinary scientific collaborations with national and international groups. We welcome enthusiastic students who dream of achieving the highest level of pharmaceutical science, natural medicine, drug discovery, and contributing to better health in human society. We have an excellent research and learning environment and can develop new skills and ideas. Every undergraduate and graduate student in our laboratory can contribute sufficiently to publishing a paper in an international journal with their name as the first author.

Campus career

テニュアトラック教員(廃止) 特命助教 2011/01/01-2015/03/31
和漢医薬学総合研究所 准教授 2015/04/01-2019/09/30
薬学・和漢系 准教授 2019/10/01-
和漢医薬学総合研究所 准教授 2019/10/01-

Affiliated academic society

The Pharmaceutical Society of Japan

Research interests

The major focus of my research is directed towards the discovery of "antiausterity strategy" based anticancer agents. These agents are useful for the treatment of pancreatic cancer, for which there is no reliable treatment at present.

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being
  • SDG 4 - Quality Education

Research Fields, Keywords

  • Drug Discovery
  • Pancreatic Cancer
  • Cancer Research
  • PI3/Akt/mTOR
  • Autophagy
  • Natural Medicine
  • Antiausterity agents
  • Screening Strategy
  • Nutrition starvation resistance
  • Drug resistance
  • ECD
  • Quantum computational Calculation
  • NMR
  • Absolute Configuration
  • Medicinal Chemistry
  • NMR structure elucidation
  • Phytochemistry
  • Chromatography

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Collaborations and top research areas from the last five years

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  • Plants (Journal)

    Awale, S. (Editor in chief)

    2018 → …

    Activity: Publication peer-review and editorial workEditorial work