Projects per year
Personal profile
Campus career
和漢医薬学総合研究所 准教授 2005/10/01-2019/09/30
薬学・和漢系 准教授 2019/10/01-
和漢医薬学総合研究所 准教授 2019/10/01-
薬学・和漢系 准教授 2019/10/01-
和漢医薬学総合研究所 准教授 2019/10/01-
Research interests
和漢薬の新しい機能性や安全性を脂質代謝の観点から明らかにすることが,本研究分野の研究課題である.機器分析による脂質成分の定量や,脂質代謝を担う分子の発現解析が,主な我々の研究手法である.特に魚油やエゴマ種子由来油脂に含まれるn-3系不飽和脂肪酸,ならびに動物胆の主成分である胆汁酸の脂質代謝に及ぼす影響や病態制御活性に関する研究を進めている.
Research Fields, Keywords
- Fatty acid
- Bile acid
- omega3
Field of expertise (Grants-in-aid for Scientific Research classification)
- General internal medicine (including psychosomatic medicine)
- Lipid nutrition
- Biological pharmacy
Fingerprint
Dive into the research topics where Shiro Watanabe is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 1 Similar Profiles
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Mechanistic elucidation of the preventive effect of pig-derived bile acids on life-related diseases through the improvement of gut barrier impairment
Watanabe, S. (Principal Investigator), 古澤之裕 (Co-Investigator(Kenkyū-buntansha)) & Tabuchi, Y. (Co-Investigator(Kenkyū-buntansha))
Japan Society for the Promotion of Science
2024/04/01 → 2027/03/31
Project: Research Project
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Experimental assessment of preventive effects of kampo medicines against metabolic syndromes through the modification of intestinal bile acid metabolism
Watanabe, S. (PI)
2018/04/01 → 2021/03/31
Project: Research
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Role of pregnane X receptor in the preventive effect of Boiogito against experimentally induced cholestatic liver injury
Watanabe, S. (PI)
2014/04/01 → 2017/03/31
Project: Research
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Detection of novel actions of kampo medicines for lipid metabolism by lipidomic analysis
Watanabe, S. (PI) & Tsuneyama, K. (CoI)
2011/04/01 → 2014/03/31
Project: Research
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Iguratimod suppresses volume-sensitive outwardly rectifying anion channels via arachidonic acid accumulation
Shimizu, T., Sumiyoshi, S., Fujita, K., Fujii, T., Toba, T., Watanabe, S. & Sakai, H., 2026/03/28, In: European Journal of Pharmacology. 1019, 178682.Research output: Contribution to journal › Article › peer-review
Open Access -
Peroxisomal ABCD1 deficiency in mice drives Th1 bias through 25-HC–LXR signaling in CD4+ T cells
Maeda, R., Oishi, M., Nagamori, R., Hikosaka-Kuniishi, M., Watanabe, S., Lee, J. B., Morita, M. & So, T., 2026, In: Frontiers in Immunology. 17, 1722647.Research output: Contribution to journal › Article › peer-review
Open Access -
Strain-Dependent Effects of Dietary Cholic Acid on Liver Fibrogenesis and Gut Microbiota in TSNO and TSOD Mice
Aoyama, T., Iwata, N., Kawamoto, S., Kato, M., Kani, K., Kasai, K., Goto, K., Yoshimoto, Y., Ichimura-Shimizu, M., Watanabe, S., Tsuneyama, K., Furusawa, Y. & Nagai, Y., 2026/02, In: Biomedicines. 14, 2, 442.Research output: Contribution to journal › Article › peer-review
Open Access -
Biomass Potential of Alkaline-Pretreated Perilla frutescens Residues and Isolation of their Degrading Bacteria
Sakatoku, A., Omori, K., Watanabe, S., Tanaka, D., Nakamura, S. & Moriwaki-Takano, M., 2025/11/20, In: Journal of Applied Glycoscience. 72, 4Research output: Contribution to journal › Article › peer-review
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Cholic Acid–Induced Akkermansia Expansion and FGF-15 Upregulation Improve Diabetes While Exacerbating Steatohepatitis in TSOD Mice
Kato, M., Goto, K., Kani, K., Igarashi, N., Kasai, K., Tada, Y., Yoshimoto, Y., Watanabe, Y., Honda, H., Ichimura-Shimizu, M., Watanabe, S., Tsuneyama, K., Furusawa, Y. & Nagai, Y., 2025/11, In: Genes to Cells. 30, 6, e70069.Research output: Contribution to journal › Article › peer-review
2 Link opens in a new tab Scopus citations
Datasets
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A New Monoterpenoid Glucoindole Alkaloid From Dipsacus asper
Li, F. (Creator), Nishidono, Y. (Creator), Tanaka, K. (Creator), Watanabe, S. (Creator) & Tezuka, Y. (Creator), SAGE Journals, 2020
DOI: 10.25384/sage.c.4936515, https://sage.figshare.com/collections/A_New_Monoterpenoid_Glucoindole_Alkaloid_From_i_Dipsacus_asper_i_/4936515
Dataset
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A New Monoterpenoid Glucoindole Alkaloid From Dipsacus asper
Li, F. (Creator), Nishidono, Y. (Creator), Tanaka, K. (Creator), Watanabe, S. (Creator) & Tezuka, Y. (Creator), SAGE Journals, 2020
DOI: 10.25384/sage.c.4936515.v1, https://sage.figshare.com/collections/A_New_Monoterpenoid_Glucoindole_Alkaloid_From_i_Dipsacus_asper_i_/4936515/1
Dataset
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CCDC 1952563: Experimental Crystal Structure Determination
Alexander, B. E. (Contributor), Sun, S. (Contributor), Palframan, M. J. (Contributor), Kociok-Köhn, G. (Contributor), Dibwe, D. F. (Contributor), Watanabe, S. (Contributor), Caggiano, L. (Contributor), Awale, S. (Contributor) & Lewis, S. E. (Contributor), Cambridge Crystallographic Data Centre, 2020
DOI: 10.5517/ccdc.csd.cc23jsxc, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc23jsxc&sid=DataCite
Dataset
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CCDC 1952564: Experimental Crystal Structure Determination
Alexander, B. E. (Contributor), Sun, S. (Contributor), Palframan, M. J. (Contributor), Kociok-Köhn, G. (Contributor), Dibwe, D. F. (Contributor), Watanabe, S. (Contributor), Caggiano, L. (Contributor), Awale, S. (Contributor) & Lewis, S. E. (Contributor), Cambridge Crystallographic Data Centre, 2020
DOI: 10.5517/ccdc.csd.cc23jsyd, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc23jsyd&sid=DataCite
Dataset
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CCDC 1952565: Experimental Crystal Structure Determination
Alexander, B. E. (Contributor), Sun, S. (Contributor), Palframan, M. J. (Contributor), Kociok-Köhn, G. (Contributor), Dibwe, D. F. (Contributor), Watanabe, S. (Contributor), Caggiano, L. (Contributor), Awale, S. (Contributor) & Lewis, S. E. (Contributor), Cambridge Crystallographic Data Centre, 2020
DOI: 10.5517/ccdc.csd.cc23jszf, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc23jszf&sid=DataCite
Dataset
Activities
- 1 social activities
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富山市環境未来都市事業における牛岳温泉熱等を活用した農業の６次産業化研究プロジェクト
Watanabe, S. (Participant)
2013/04 → …Activity: Other › social activities
Courses
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応用和漢医薬学特論
Watanabe, S., Tohda, C., Morita, H., Hayakawa, Y., Awale, S., Nakagawa, Y., Kim, J. & Oku, M. 2025/12/05 → 2026/03/31
Course
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専門英語Ⅱ（生体防御学領域）
Sakurai, H., Watanabe, S., Hayakawa, Y., Susukida, T. & Sasaki, S. 2025/10/01 → 2026/03/31
Course
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卒業研究（生体防御学領域）薬6年用
Sakurai, H., Watanabe, S., Hayakawa, Y., Susukida, T. & Sasaki, S. 2025/04/01 → 2026/03/31
Course
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東西医薬学Ⅰ
Kato, A., Watanabe, S., Tohda, C., Koizumi, K., Morita, H., Hayakawa, Y., Awale, S., Nakagawa, Y., Kim, J., Oku, M., Jo, M., Sasaki, S., Nakashima, Y. & Shoji, T. 2025/04/01 → 2025/09/30
Course
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卒業研究（生体防御学領域）創薬4年用
Sakurai, H., Watanabe, S., Hayakawa, Y., Susukida, T. & Sasaki, S. 2025/04/01 → 2026/03/31
Course