Personal profile
Campus career
薬学科 教授 2006/04/01-2019/09/30
薬学系 教授 2006/04/01-2019/09/30
大学院医学薬学教育部 部長（学部長含む） 2013/10/01-2014/03/31
薬学部 部長（学部長含む） 2013/10/01-2018/03/31
大学院医学薬学研究部 部長（学部長含む） 2014/04/01-2016/03/31
大学院医学薬学教育部 部長（学部長含む） 2016/04/01-2018/03/31
学長補佐 2018/4/1-2019/3/31
副学長・附属図書館 館長 2019/04/01-2023/3/31
薬学・和漢系 教授 2019/10/01-
大学院医薬理工学環長 2022/4/1-
薬学部薬学科 基幹教員
学部運営への参画状況・・・有-教授会
担当授業科目に係る状況・・・主要授業科目担当
Qualification
Affiliated academic society
American Association of Pharmaceutical Scientists (AAPS) : 1994/01-
Association for Research in Vision and Ophthalmology (ARVO) : 1995/01-
日本薬学会 所属期間：1983/01-
日本DDS学会 所属期間：1987/01-
薬物動態学会 所属期間：1998/05-
日本薬剤学会 所属期間：1999/01-
Research Fields, Keywords
- Blood-retinal barrier transport
Field of expertise (Grants-in-aid for Scientific Research classification)
- Medical pharmacy
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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網膜関門輸送機構解明に基づく新規網膜治療シーズの薬理最大化を実現する投与計画立案
Hosoya, K.-I. (Principal Investigator)
Japan Society for the Promotion of Science
2026/04/01 → 2029/03/31
Project: Research Project
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脳クレアチン供給を実現するモノカルボン酸輸送体認識型プロドラッグ開発とその有用性
Hosoya, K.-I. (Principal Investigator), 立川正憲 (Co-Investigator(Kenkyū-buntansha)), Toyooka, N. (Co-Investigator(Kenkyū-buntansha)) & Akanuma, S.-I. (Co-Investigator(Kenkyū-buntansha))
Japan Society for the Promotion of Science
2023/04/01 → 2026/03/31
Project: Research Project
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Transport mechanisms of cell-penetrating peptides at the blood-retinal barrier to establish strategies of macromolecular drug delivery
Akanuma, S.-I. (Principal Investigator), 泉尾直孝 (Co-Investigator(Kenkyū-buntansha)) & Hosoya, K.-I. (Co-Investigator(Kenkyū-buntansha))
Japan Society for the Promotion of Science
2022/04/01 → 2025/03/31
Project: Research Project
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Involvement of monocarboxylate transporter 7 in taurine efflux transport from rat retinal pericytes and capillary endothelial cells
Tega, Y., Kusakabe, F., Akanuma, S. I. & Hosoya, K. I., 2026/01, In: Microvascular Research. 163, 104876.Research output: Contribution to journal › Article › peer-review
Open Access -
Role of P-glycoprotein in attenuation of retinal amyloid-β peptide (1–40) clearance across the rat inner blood-retinal barrier induced by lipopolysaccharide
Daikohara, K., Akanuma, S. I., Tega, Y. & Hosoya, K. I., 2026/01, In: Experimental Eye Research. 262, 110759.Research output: Contribution to journal › Article › peer-review
Open Access -
Decrease in In Vivo Efflux Transport via P-glycoprotein at the Rat Inner Blood-Retinal Barrier by Peripheral Administration of Lipopolysaccharide
Daikohara, K., Akanuma, S. I., Kawanishi, M., Tega, Y. & Hosoya, K. I., 2025/06, In: Pharmaceutical Research. 42, 6, p. 907-915 9 p.Research output: Contribution to journal › Article › peer-review
1 Link opens in a new tab Scopus citations -
Identification of Rat Monocarboxylate Transporter 9 as a Low-Affinity Transporter of 1-Methyl-4-phenylpyridinium and Amantadine
Shinozaki, Y., Miki, S., Kubo, Y., Tega, Y., Akanuma, S. I. & Hosoya, K. I., 2025/12/19, In: Biological and Pharmaceutical Bulletin. 48, 12, p. 1947-1951 5 p.Research output: Contribution to journal › Review article › peer-review
Open Access -
In vitro characterization of taurine transport using the human brain microvascular endothelial cell line as a human blood-brain barrier model
Tega, Y., Kawauchi, Y., Akanuma, S. I., Inagaki, M., Tachikawa, M. & Hosoya, K. I., 2025/04, In: Drug Metabolism and Pharmacokinetics. 61, 101040.Research output: Contribution to journal › Article › peer-review
Open Access7 Link opens in a new tab Scopus citations
Datasets
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Processing mechanism of guanidinoacetate in choroid plexus epithelial cells: conversion of guanidinoacetate to creatine via guanidinoacetate N-methyltransferase and monocarboxylate transporter 12-mediated creatine release into the CSF
Jomura, R. (Creator), Akanuma, S.-I. (Creator), Kubo, Y. (Creator), Tachikawa, M. (Creator) & Hosoya, K.-I. (Creator), figshare, 2022
DOI: 10.6084/m9.figshare.c.6030313, https://springernature.figshare.com/collections/Processing_mechanism_of_guanidinoacetate_in_choroid_plexus_epithelial_cells_conversion_of_guanidinoacetate_to_creatine_via_guanidinoacetate_N-methyltransferase_and_monocarboxylate_transporter_12-mediated_creatine_release_into_the_CSF/6030313
Dataset
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Processing mechanism of guanidinoacetate in choroid plexus epithelial cells: conversion of guanidinoacetate to creatine via guanidinoacetate N-methyltransferase and monocarboxylate transporter 12-mediated creatine release into the CSF
Jomura, R. (Creator), Akanuma, S.-I. (Creator), Kubo, Y. (Creator), Tachikawa, M. (Creator) & Hosoya, K.-I. (Creator), figshare, 2022
DOI: 10.6084/m9.figshare.c.6030313.v1, https://springernature.figshare.com/collections/Processing_mechanism_of_guanidinoacetate_in_choroid_plexus_epithelial_cells_conversion_of_guanidinoacetate_to_creatine_via_guanidinoacetate_N-methyltransferase_and_monocarboxylate_transporter_12-mediated_creatine_release_into_the_CSF/6030313/1
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Courses
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ファーマ・メディカルバイオ序論
Hosoya, K.-I., Okada, K., Tabata, T., Tohda, C. & Takao, K. 2024/10/02 → 2024/12/03
Course
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