Personal profile
Campus career
Qualification
放射線取扱主任者（第１種）
薬剤師
Affiliated academic society
Research interests
Education/Academic qualification
東京大学大学院薬学系研究科（論文博士取得）
1999/01
岡山大学大学院薬学研究科製薬化学専攻
1990/04/01 → 1992/03/31
岡山大学薬学部製薬化学科
1986/04/01 → 1990/03/31
兵庫県立星陵高等学校
1982/04/01 → 1985/03/31
Field of expertise (Grants-in-aid for Scientific Research classification)
- Biological pharmacy
- Tumor biology
Fingerprint
- 1 Similar Profiles
Projects
- 6 Finished
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Cancer pathophysiology and treatment from the perspective of dual-mode control of EGFR
Sakurai, H. (PI), Hayashi, R. (CoPI), 越，横山 悟，櫻井 宏明石田勝也，福司弥生，周 (CoPI) & Yokoyama, S. (CoPI)
2022/04/01 → 2025/03/31
Project: Research
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Alternative activation mechanisms of receptor tyrosine kinases in inflammation-induced cancer progression
Sakurai, H. (PI)
2019/04/01 → 2022/03/31
Project: Research
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Functional interactions between inflammatory signal and growth singaling in the Warburg effect in cancer cells
Sakurai, H. (PI)
2016/04/01 → 2018/03/31
Project: Research
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Noncanonical activation of receptor tyrosine kinases: next target mechanisms for cancer progression
Sakurai, H. (PI), Ozawa, T. (CoI) & Kawasaki, Y. (CoI)
2016/04/01 → 2019/03/31
Project: Research
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Role of TNF-TAK1 signaling pathway in tumor microenvironments of metastasis
Sakurai, H. (PI) & Saiki, I. (CoPI)
2011/04/28 → 2015/03/31
Project: Research
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IκB kinases phosphorylate NF-κB p65 subunit on serine 536 in the transactivation domain
Sakurai, H., Chiba, H., Miyoshi, H., Sugita, T. & Toriumi, W., 1999/10/22, In: Journal of Biological Chemistry. 274, 43, p. 30353-30356 4 p.Research output: Contribution to journal › Article › peer-review
Open Access759 Link opens in a new tab Scopus citations -
Targeting of TAK1 in inflammatory disorders and cancer
Sakurai, H., 2012/10, In: Trends in Pharmacological Sciences. 33, 10, p. 522-530 9 p.Research output: Contribution to journal › Review article › peer-review
341 Link opens in a new tab Scopus citations -
Functional interactions of transforming growth factor β-activated kinase I with IκB kinases to stimulate NF-κB activation
Sakurai, H., Miyoshi, H., Toriumi, W. & Sugita, T., 1999/04/09, In: Journal of Biological Chemistry. 274, 15, p. 10641-10648 8 p.Research output: Contribution to journal › Article › peer-review
Open Access208 Link opens in a new tab Scopus citations -
Crucial roles of RSK in cell motility by catalysing serine phosphorylation of EphA2
Zhou, Y., Yamada, N., Tanaka, T., Hori, T., Yokoyama, S., Hayakawa, Y., Yano, S., Fukuoka, J., Koizumi, K., Saiki, I. & Sakurai, H., 2015/07/09, In: Nature Communications. 6, 7679.Research output: Contribution to journal › Article › peer-review
Open Access132 Link opens in a new tab Scopus citations -
Ligand-activated epidermal growth factor receptor (EGFR) signaling governs endocytic trafficking of unliganded receptor monomers by non-canonical phosphorylation
Tanaka, T., Zhou, Y., Ozawa, T., Okizono, R., Banba, A., Yamamura, T., Oga, E., Muraguchi, A. & Sakurai, H., 2018/02/16, In: Journal of Biological Chemistry. 293, 7, p. 2288-2301 14 p.Research output: Contribution to journal › Article › peer-review
Open Access59 Link opens in a new tab Scopus citations
Datasets
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CCDC 188549: Experimental Crystal Structure Determination
Ishihara, K. (Contributor), Kawaguchi, T. (Contributor), Matsuya, Y. (Contributor), Sakurai, H. (Contributor), Saiki, I. (Contributor) & Nemoto, H. (Contributor), Cambridge Crystallographic Data Centre, 2005
DOI: 10.5517/cc6b67y, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/cc6b67y&sid=DataCite
Dataset
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Identification of genes that are regulated by TAK1 in human cutaneous T cell lymphoma HuT-102 cells
Suzuki, S. (Contributor), Zhou, Y. (Contributor), Refaat, A. (Contributor), Takasaki, I. (Contributor), Koizumi, K. (Contributor), Yamaoka, S. (Contributor), Tabuchi, Y. (Contributor), Saiki, I. (Contributor) & Sakurai, H. (Contributor), ArrayExpress, 2009
https://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-16219
Dataset
Prizes
Activities
- 1 Oral presentation
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シンポジウム「次世代型がん治療法の創製に向けた基礎薬学研究のフロントライン」
Sakurai, H. (Speaker)
2019/03/20 → 2019/03/23Activity: Talk or presentation › Oral presentation