Projects per year
Personal profile
Campus career
東西統合医学系 教授 2011/01/16-2019/09/30
薬学・和漢系 教授 2019/10/01-
薬学科 教授 2019/10/01-
薬学部薬学科 基幹教員
学部運営への参画状況・・・有-教授会
担当授業科目に係る状況・・・主要授業科目担当
Affiliated academic society
日本臨床薬理学会 所属期間:2002/11-
日本TDM学会 所属期間:2004/05-
日本医療薬学会 所属期間:2004/08-
日本リウマチ学会 所属期間:2005/09-
日本薬剤学会 所属期間:2007/02-
日本時間生物学会 所属期間:2007/04-
日本臨床腫瘍学会 所属期間:2007/08-
日本癌学会 所属期間:2009/07-
日本薬理学会 所属期間:2010/09-
富山県薬剤師会 所属期間:2011/02-
和漢医薬学会 所属期間:2013/08-
Research interests
これらを解決する方法として,主に“生体リズム"に着目しています.生体機能の様々な周期性はヒトを始めとする多くの生物で存在します.特に,概日リズムは疾患や病状にも存在し,一日の中で発作など発症しやすい時間帯が知られています. そこで,“投薬タイミング"を操作するという簡潔・明快な方法によって,現在の治療法と比較しても治療成績の向上が期待できる時間薬物療法を,多くの疾患に臨床応用できるようにしたいと考え,基礎研究や臨床研究を行っています.
Research Fields, Keywords
- chronotherapy
- clinical pharmacology
Field of expertise (Grants-in-aid for Scientific Research classification)
- Chronopharmacology
- Clinical Pharmacology
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Collaborations and top research areas from the last five years
Projects
- 7 Finished
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Application of chronotherapy to decrease the drug-induced peripheral neuropathy
To, H. (PI)
2016/04/01 → 2019/03/31
Project: Research
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Application of chronotherapy of antirheumatic drug to perform proper therapy
To, H. (PI)
2012/04/01 → 2014/03/31
Project: Research
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Population pharmacokinetic analysis identifies an absorption process model for mycophenolic acid in patients with renal transplant
Suzuki, Y., Matsunaga, N., Aoyama, T., Ogami, C., Hasegawa, C., Iida, S., To, H., Kitahara, T. & Tsuji, Y., 2024/12, In: Clinical and Translational Science. 17, 12, e70097.Research output: Contribution to journal › Article › peer-review
Open Access -
Comparison of the efficacy of anti-diabetic medications as add-on to metformin in type 2 diabetes mellitus from a real-world database
Ono, R., Ogami, C., Hasegawa, C., To, H., Matsumoto, Y. & Tsuji, Y., 2023/12, In: BMC Pharmacology and Toxicology. 24, 1, 75.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Population Pharmacokinetic Model for Unbound Concentrations of Daptomycin in Patients with MRSA Including Patients Undergoing Hemodialysis
Takahashi, S., Tsuji, Y., Holford, N., Ogami, C., Kasai, H., Kawasuji, H., To, H. & Yamamoto, Y., 2023/03, In: European Journal of Drug Metabolism and Pharmacokinetics. 48, 2, p. 201-211 11 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Time dependent cisplatin dosing differences on hypoalgesia focusing on oxidative stress
Seto, Y., Niwa, K., Okazaki, F. & To, H., 2023/03/05, In: European Journal of Pharmacology. 942, 175519.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Development of In Vitro Evaluation System for Assessing Drug Dissolution Considering Physiological Environment in Nasal Cavity
Inoue, D., Yamashita, A. & To, H., 2022/11, In: Pharmaceutics. 14, 11, 2350.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations
Datasets
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Influence of dosing times on cisplatin-induced peripheral neuropathy in rats
Seto, Y. (Creator), Okazaki, F. (Creator), Horikawa, K. (Creator), Zhang, J. (Creator), Sasaki, H. (Creator) & To, H. (Creator), figshare, 2016
DOI: 10.6084/m9.figshare.c.3630242, https://springernature.figshare.com/collections/Influence_of_dosing_times_on_cisplatin-induced_peripheral_neuropathy_in_rats/3630242
Dataset
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Additional file 3: of Influence of dosing times on cisplatin-induced peripheral neuropathy in rats
Seto, Y. (Creator), Okazaki, F. (Contributor), Horikawa, K. (Creator), Zhang, J. (Creator), Sasaki, H. (Creator) & To, H. (Creator), figshare, 2016
DOI: 10.6084/m9.figshare.c.3630242_d1, https://springernature.figshare.com/articles/presentation/Additional_file_3_of_Influence_of_dosing_times_on_cisplatin-induced_peripheral_neuropathy_in_rats/4421537
Dataset
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Additional file 3: of Influence of dosing times on cisplatin-induced peripheral neuropathy in rats
Seto, Y. (Creator), Okazaki, F. (Contributor), Horikawa, K. (Creator), Zhang, J. (Creator), Sasaki, H. (Creator) & To, H. (Creator), figshare, 2016
DOI: 10.6084/m9.figshare.c.3630242_d1.v1, https://springernature.figshare.com/articles/presentation/Additional_file_3_of_Influence_of_dosing_times_on_cisplatin-induced_peripheral_neuropathy_in_rats/4421537/1
Dataset
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Additional file 2: of Influence of dosing times on cisplatin-induced peripheral neuropathy in rats
Seto, Y. (Creator), Okazaki, F. (Contributor), Horikawa, K. (Creator), Zhang, J. (Creator), Sasaki, H. (Creator) & To, H. (Creator), figshare, 2016
DOI: 10.6084/m9.figshare.c.3630242_d3.v1, https://springernature.figshare.com/articles/presentation/Additional_file_2_of_Influence_of_dosing_times_on_cisplatin-induced_peripheral_neuropathy_in_rats/4421573/1
Dataset
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Influence of dosing times on cisplatin-induced peripheral neuropathy in rats
Seto, Y. (Creator), Okazaki, F. (Creator), Horikawa, K. (Creator), Zhang, J. (Creator), Sasaki, H. (Creator) & To, H. (Creator), figshare, 2016
DOI: 10.6084/m9.figshare.c.3630242.v1, https://springernature.figshare.com/collections/Influence_of_dosing_times_on_cisplatin-induced_peripheral_neuropathy_in_rats/3630242/1
Dataset
Prizes
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b 生体リズムを基盤とした抗リウマチ薬の至適投与法の構築 /b
To, H. (Speaker)
2016Activity: Talk or presentation › Oral presentation
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Courses
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医薬品薬効動態学実習
Hosoya, K.-I., Tabuchi, A., Nitta, A., Sasaoka, T., Hashimoto, Y., To, H., Akanuma, S.-I., So, T., Kume, T., Sakurai, H., Watanabe, S., Shibahara, N., Tohda, C., Koizumi, K., Hayakawa, Y., Nakagawa, Y. & Kim, J. 2024/10/01 → 2025/03/31
Course
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医薬品薬効動態学実習
Hosoya, K.-I., Tabuchi, A., Nitta, A., Sasaoka, T., Hashimoto, Y., To, H., Akanuma, S.-I., So, T., Kume, T., Sakurai, H., Watanabe, S., Shibahara, N., Tohda, C., Koizumi, K., Hayakawa, Y., Nakagawa, Y. & Kim, J. 2024/10/01 → 2025/03/31
Course
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