Projects per year
Personal profile
Campus career
医学科 助教 2011/01/01-2019/09/30
環境生体防御医学系 助教 2011/01/01-2019/09/30
医学系 助教 2019/10/01-
医学科 助教 2019/10/01-
医学部医学科 基幹教員
学部運営への参画状況・・・有-教授会
担当授業科目に係る状況・・・主要授業科目担当
環境生体防御医学系 助教 2011/01/01-2019/09/30
医学系 助教 2019/10/01-
医学科 助教 2019/10/01-
医学部医学科 基幹教員
学部運営への参画状況・・・有-教授会
担当授業科目に係る状況・・・主要授業科目担当
Research interests
抗原特異的T細胞の1個1個からT細胞のセンサーであるT細胞受容体遺伝子をクローニングし,その遺伝子の抗原特異性を評価するまでを10日間という極めて短期間で行うシステムを確立した.このシステムを用い,新たながんや感染症の治療法の開発を行っている.
Research Fields, Keywords
- Immunology
Field of expertise (Grants-in-aid for Scientific Research classification)
- Immunology
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Projects
- 6 Finished
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Identification of antigens of tumor-infiltrated regulatory T cells and analysis of tumor suppression systems based on the antigens
Kobayashi, E. (PI)
2018/04/01 → 2021/03/31
Project: Research
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Development of Zika fever- and AIDS-peptide vaccine using next generation chip, T-ISAAC
Muraguchi, A. (PI), Kishi, H. (CoI), Ozawa, T. (CoI), Kobayashi, E. (CoI) & Udaka, K. (CoI)
2017/04/01 → 2020/03/31
Project: Research
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Development of an innovative lymphocyte chip to establish personalized immuno-therapy for infectious diseases
Muraguchi, A. (PI), Kishi, H. (CoI), Ozawa, T. (CoI), Hamana, H. (CoI) & Kobayashi, E. (CoI)
2014/04/01 → 2017/03/31
Project: Research
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Detection of cancer specific T cells on a chip
Kishi, H. (PI), Muraguchi, A. (CoI), Ozawa, T. (CoI), Kobayashi, E. (CoI), Kaneko, S. (CoI) & Mizukoshi, E. (CoI)
2012/04/01 → 2014/03/31
Project: Research
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Development of a Novel CD26-Targeted Chimeric Antigen Receptor T-Cell Therapy for CD26-Expressing T-Cell Malignancies
Kobayashi, E., Kamihara, Y., Arai, M., Wada, A., Kikuchi, S., Hatano, R., Iwao, N., Susukida, T., Ozawa, T., Adachi, Y., Kishi, H., Dang, N. H., Yamada, T., Hayakawa, Y., Morimoto, C. & Sato, T., 2023/08, In: Cells. 12, 16, 2059.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
DPP8 Selective Inhibitor Tominostat as a Novel and Broad-Spectrum Anticancer Agent against Hematological Malignancies
Kikuchi, S., Wada, A., Kamihara, Y., Okazaki, K., Jawaid, P., Rehman, M. U., Kobayashi, E., Susukida, T., Minemura, T., Nabe, Y., Iwao, N., Ozawa, T., Hatano, R., Yamada, M., Kishi, H., Matsuya, Y., Mizuguchi, M., Hayakawa, Y., Dang, N. H. & Sakamoto, Y. & 2 others, , 2023/04/06, In: Cells. 12, 7Research output: Contribution to journal › Article › peer-review
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DPP8 Selective Inhibitor Tominostat as a Novel and Broad-Spectrum Anticancer Agent against Hematological Malignancies
Kikuchi, S., Wada, A., Kamihara, Y., Okazaki, K., Jawaid, P., Rehman, M. U., Kobayashi, E., Susukida, T., Minemura, T., Nabe, Y., Iwao, N., Ozawa, T., Hatano, R., Yamada, M., Kishi, H., Matsuya, Y., Mizuguchi, M., Hayakawa, Y., Dang, N. H. & Sakamoto, Y. & 2 others, , 2023/04, In: Cells. 12, 7, 1100.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Gene modified NK cell line as a powerful tool for evaluation of cloned TCRs for TCR-T cell therapy
Kobayashi, E., Ozawa, T., Hamana, H., Muraguchi, A. & Kishi, H., 2023/01, In: Cellular Immunology. 383, 104656.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
N-glycan in the monoclonal ACPA, CCP-Ab1 the variable region promotes the exacerbation of experimental arthritis
Kawataka, M., Ouhara, K., Kobayashi, E., Shinoda, K., Tobe, K., Fujimori, R., Mizuno, N., Sugiyama, E., Ozawa, T. & Kishi, H., 2023/03/21, (E-pub ahead of print) In: Rheumatology (United Kingdom).Research output: Contribution to journal › Article › peer-review
1 Scopus citations
Activities
- 6 Oral presentation
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Cloning and functional analysis of human telomerase reverse transcriptase (hTERT)-specific TCRs from peptide-vaccinated patients
Kobayashi, E. (Speaker)
2013/11/11 → 2013/11/13Activity: Talk or presentation › Oral presentation
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A novel cloning system of human antigen-specific TCRs can confer the candidates for cancer gene therapy
Kobayashi, E. (Speaker)
2013/10/03 → 2013/10/05Activity: Talk or presentation › Oral presentation
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Cloning of human antigen-specific TCRs can confer the candidates for cancer gene therapy
Kobayashi, E. (Speaker)
2013/08/22 → 2013/08/27Activity: Talk or presentation › Oral presentation
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A novel human TCR efficient cloning system confers candidate for TCR gene therapy within 10 days
Kobayashi, E. (Speaker)
2012/10/26 → 2012/10/28Activity: Talk or presentation › Oral presentation
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抗原特異的T細胞受容体遺伝子の超迅速クローニングシステムの構築
Kobayashi, E. (Speaker)
2012/07/26 → 2012/07/28Activity: Talk or presentation › Oral presentation