Projects per year
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. Our work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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Profiles
Projects
- 10 Finished
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Analyses of essential interactions of iminosugars with the Hex A active site and evaluation of their pharmacological chaperone effects for Tay-Sachs disease
Kato, A. (PI)
2017/04/01 → 2020/03/31
Project: Research
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Strategy for designing selective rhamnosidase inhibitors: Synthesis and biological evaluation of L-DMDP cyclic isothioureas
Adachi, I. (PI), Kato, A. (CoI) & Natori, Y. (CoI)
2015/04/01 → 2018/03/31
Project: Research
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Enantiomeric C-6 fluorinated swainsonine derivatives as highly selective and potent inhibitors of α-mannosidase and α-L-rhamnosidase: Design, synthesis and structure-activity relationship study
Gao, F.-T., Zhang, M., Shimadate, Y., Kato, A., Li, Y.-X., Jia, Y.-M. & Yu, C.-Y., 2025/01/01, In: European Journal of Medicinal Chemistry. 282, p. 117031Research output: Contribution to journal › Article › peer-review
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Synthesis of 8-epi-L-swainsonine, related C6 alkylated derivatives and their α-L-rhamnosidase inhibition
Shimadate, Y., Oshima, S., Kasamatsu, N., Yamamoto, S., Taguchi, A., Nash, R. J., Fleet, G. W. J., Okada, T., Toyooka, N. & Kato, A., 2024/03/01, In: Tetrahedron Letters. p. 155008Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Distinctive accumulation of globotriaosylceramide and globotriaosylsphingosine in a mouse model of classic Fabry disease
Taguchi, A., Ishii, S., Mikame, M. & Maruyama, H., 2023/03, In: Molecular Genetics and Metabolism Reports. 34, 100952.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations
Prizes
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Tetrahedron: Asymmetry: Top-25 Most Cited Articles 2010-2011 Award
Kato, A. (Recipient), 2012/01
Prize
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Tetrahedron: Asymmetry: Top-25 Most Cited Articles 2010-2011 Award
Kato, A. (Recipient), 2012/01
Prize
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植物由来化合物の機能性化粧品素材への応用：Ginnalin B の生物活性に関する研究
Kenta Shinzawa (Speaker)
2022/10/16Activity: Talk or presentation › Oral presentation
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5-C-分岐型デオキシノジリマイシンを基盤としたGAA高親和性シャペロンのデザイン研究
Kenta Shinzawa (Speaker)
2022/10/01Activity: Talk or presentation › Oral presentation
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In silico解析と親和性測定に基づいたlysosomal acid α-glucosidase (GAA)選択特性を有するイミノ糖のデザイン研究
Kenta Shinzawa (Speaker)
2022/03/28Activity: Talk or presentation › Oral presentation