Projects per year
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. Our work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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Profiles
Projects
- 16 Finished
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Structural study of pro-filaggrin recognition by SASPase
Obita, T. (PI)
2020/04/01 → 2023/03/31
Project: Research
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PQBP1はcGASによるI型インターフェロンの発現誘導をどのように抑制するのか
Mizuguchi, M. (PI) & Obita, T. (CoI)
2019/04/01 → 2022/03/31
Project: Research
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Development of a selective BRD4 inhibitor by neutron protein crystallographic analysis
Yokoyama, T. (PI)
2019/04/01 → 2022/03/31
Project: Research
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Development of Benziodarone Analogues with Enhanced Potency for Selective Binding to Transthyretin in Human Plasma
Mizuguchi, M., Nakagawa, Y., Yokoyama, T., Okada, T., Fujii, K., Takahashi, K., Luan, N. N. T., Nabeshima, Y., Kanamitsu, K., Nakagawa, S., Yamakawa, S., Ueda, M., Ando, Y. & Toyooka, N., 2024/05/09, In: Journal of Medicinal Chemistry. 67, 9, p. 6987-7005 19 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Enzymatic activity of cGAS in the presence of three types of DNAs: limited cGAS stimulation by single-stranded HIV-1 SL2 DNA
Mizuguchi, M., Kyan, N., Nishimata, S., Nabeshima, Y. & Obita, T., 2024/04, In: Bioscience Reports. 44, 4, BSR20240269.Research output: Contribution to journal › Article › peer-review
Open Access -
SIRT5 mutants reveal the role of conserved asparagine and glutamine residues in the NAD+-binding pocket
Yokoyama, T., Takayama, Y., Mizuguchi, M., Nabeshima, Y. & Kusaka, K., 2024/09, In: FEBS Letters. 598, 18, p. 2269-2280 12 p.Research output: Contribution to journal › Article › peer-review